Evidence map›Paper›PMID 39803844›Full record

ArticleMacromolecular bioscience2025

Characterization of Thin Polymer Layer Prepared from Liposomes and Polyelectrolytes for TGF-β

Nils Meier, Leonie Berten-Schunk, Yvonne Roger, Robert Hänsch, Andrea Hoffmann, Heike Bunjes, Wibke Dempwolf, Henning Menzel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Macromolecular bioscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nils MeierInstitute for Technical Chemistry, Macromolecular Chemistry, TU Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.ORCID 0000-0001-5343-8506
Leonie Berten-SchunkInstitute of Pharmaceutical Technology and Biopharmaceutics, TU Braunschweig, Mendelssohnstrasse 1, 38106, Braunschweig, Germany.ORCID 0009-0001-9920-2539
Yvonne RogerDepartment of Orthopedic Surgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.ORCID 0000-0002-8775-5320
Robert HänschInstitute of Plant Biology, TU Braunschweig, Humboldtstraße 1, 38106, Braunschweig, Germany.ORCID 0000-0003-1310-8419
Andrea HoffmannDepartment of Orthopedic Surgery, Hannover Medical School, Carl-Neuberg-Straße 1, 30625, Hannover, Germany.ORCID 0000-0003-2318-8985
Heike BunjesInstitute of Pharmaceutical Technology and Biopharmaceutics, TU Braunschweig, Mendelssohnstrasse 1, 38106, Braunschweig, Germany.ORCID 0000-0002-8670-6076
Wibke DempwolfInstitute for Technical Chemistry, Macromolecular Chemistry, TU Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.
Henning MenzelInstitute for Technical Chemistry, Macromolecular Chemistry, TU Braunschweig, Hagenring 30, 38106, Braunschweig, Germany.ORCID 0000-0002-4915-7311

Funding

Deutsche Forschungsgemeinschaft 251503496Deutsche Forschungsgemeinschaft 269986331Deutsche Forschungsgemeinschaft 270206734
6 · The paper itself

Abstract

Implant-integrated drug delivery systems that enable the release of biologically active factors can be part of an in situ tissue engineering approach to restore biological function. Implants can be functionalized with drug-loaded nanoparticles through a layer-by-layer assembly. Such coatings can release biologically active levels of growth factors. Sustained release is desired for many in vivo applications. The layer-by-layer technique also allows for the addition of extra layers, which can serve as "barriers" to delay the release. Electrospun Polycaprolactone (PCL) fiber mats are modified with a Chitosan (CS) grafted with PCL sidechains (CS-g-PCL

Indexed as

LiposomesPolyelectrolytesTissue EngineeringTransforming Growth Factor beta3ChitosanDrug Delivery SystemsDrug LiberationHumansNanoparticlesPolyestersChitosanLiposomespolycaprolactonePolyelectrolytesPolyestersTransforming Growth Factor beta3layer‐by‐layer build‐upsurfaces modification and functionalizationTGF β3 releasetissue engineering

Identifiers

PMID39803844
PMCPMC11995839

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.