Evidence map›Paper›PMID 39803810›Full record

ArticleJournal of periodontal research2025

Incidence and Risk Factors of Peri-Implantitis Over Time-A Prospective Cohort Study.

Mario Romandini, Cristina Lima, Diogo Banaco, Rita Azevedo, Mariano Sanz

Abstract read
In one paragraph

Article in Journal of periodontal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Review
  5. Article
  6. Bone Grafts: Everything You Need to Know.Journal of periodontal research · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mario RomandiniSection of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.ORCID https://orcid.org/0000-0001-5646-083X
Cristina LimaSection of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.
Diogo BanacoSection of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.
Rita AzevedoSection of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.
Mariano SanzSection of Periodontology, Faculty of Odontology, University Complutense, Madrid, Spain.ORCID https://orcid.org/0000-0002-6293-5755

Funding

Eklund Foundation
6 · The paper itself

Abstract

aimThis prospective cohort study aimed to evaluate the incidence and risk/protective factors of peri-implantitis over time.

methodsA university-representative cohort was evaluated at baseline and after a mean follow-up time of 3.9 years. The main outcome was the incidence of peri-implantitis, defined as bone loss > 1 mm between the two examinations in implants showing bleeding on probing. Putative risk/protective factors assessed at baseline were tested through multilevel (mixed-effects) logistic regression analyses.

resultsA total of 73 patients with 322 implants were included. During the follow-up period, 14 implants (4.3%) were lost in 9 patients (12.3%). Incidence of peri-implantitis was observed in 22.2% of patients and 9.4% of implants. In the final multilevel multiple logistic regression model, the following factors were associated with occurrence of peri-implantitis: periodontitis severity (stage IV periodontitis: OR = 41.29; 95% CI: 4.10-415.54), periodontal bone loss/age ratio (> 1: OR = 8.87; 95% CI: 1.47-53.73), smoking (current smokers: OR = 7.84; 95% CI: 1.83-33.50), sleep duration (> 7 h: OR = 19.97; 95% CI: 1.69-236.39), implant location (incisor: OR = 60.60; 95% CI: 4.04-908.33), restoration type (full-arch fixed restorations: OR = 89.84; 95% CI: 3.66-2202.97), and restoration margin location (juxta-marginal: OR = 14.17; 95% CI: 1.20-166.76). Keratinized tissue width assessed at baseline was not associated with incidence of peri-implantitis.

conclusionApproximately one in five patients and one in 10 implants experienced incident peri-implantitis over a nearly four-year period. Periodontitis (Stage IV and Grade C), lifestyles (smoking and sleep duration), implant location, and prosthetic factors (restoration type and margin location) emerged as risk factors for peri-implantitis.

Indexed as

Peri-ImplantitisAdultAgedAlveolar Bone LossFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPeriodontitisProspective StudiesRisk FactorsSmokingTime Factorsdental implantsdental prosthesisepidemiologic factorsepidemiologymaintenanceperi‐implant diseasesperiodontal diseases

Identifiers

PMID39803810
PMCPMC12881879

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.