Evidence map›Paper›PMID 39803779›Full record

ArticleActa physiologica (Oxford, England)2025

Machine learning-based blood pressure estimation using impedance cardiography data.

T L Bothe, A Patzak, O S Opatz, V Heinz, N Pilz

Abstract read
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Article in Acta physiologica (Oxford, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

T L BotheInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0001-7569-4527
A PatzakInstitute of Translational Physiology, Charité-Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-1088-6875
O S OpatzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.
V HeinzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.
N PilzInstitute of Physiology, Center for Space Medicine and Extreme Environments Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Funding

BMWK (German Federal Ministry for Economic Affairs and Climate Action) 16SV9251DLR (German Aerospace Center, Bonn, Germany) 331 50WB2330
6 · The paper itself

Abstract

objectiveAccurate blood pressure (BP) measurement is crucial for the diagnosis, risk assessment, treatment decision-making, and monitoring of cardiovascular diseases. Unfortunately, cuff-based BP measurements suffer from inaccuracies and discomfort. This study is the first to access the feasibility of machine learning-based BP estimation using impedance cardiography (ICG) data.

methodsWe analyzed ICG data from 71 young and healthy adults. Nine different machine learning algorithms were evaluated for their BP estimation performance against quality controlled, oscillometric (cuff-based), arterial BP measurements during mental (Trier social stress test), and physical exercise (bike ergometer). Models were optimized to minimize the root mean squared error and their performance was evaluated against accuracy and regression metrics.

resultsThe multi-linear regression model demonstrated the highest measurement accuracy for systolic BP with a mean difference of -0.01 mmHg, a standard deviation (SD) of 10.79 mmHg, a mean absolute error (MAE) of 8.20 mmHg, and a correlation coefficient of r = 0.82. In contrast, the support vector regression model achieved the highest accuracy for diastolic BP with a mean difference of 0.15 mmHg, SD = 7.79 mmHg, MEA = 6.05 mmHg, and a correlation coefficient of r = 0.51.

conclusionThe study demonstrates the feasibility of ICG-based machine learning algorithms for estimating cuff-based reference BP. However, further research into limiting biases, improving performance, and standardized validation is needed before clinical use.

Indexed as

Blood PressureBlood Pressure DeterminationCardiography, ImpedanceMachine LearningAdultFemaleHumansMaleYoung Adultblood pressureblood pressure measurementcardiovascular riskdeep learningimpedance cardiographymachine learningphysiology

Identifiers

PMID39803779
PMCPMC11726408

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.