Evidence map›Paper›PMID 39803352›Full record

ArticleVeterinary medicine international2025

Molecular Characterization of Bovine

Nader Maher Sobhy, Walid Refaai, Rahul Kumar, Christiana Rezk Bottros Youssef, Sagar Mal Goyal

Abstract read
In one paragraph

Article in Veterinary medicine international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nader Maher SobhyDepartment of Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Sharkia 44511, Egypt.ORCID https://orcid.org/0000-0002-9834-9627
Walid RefaaiDepartment of Surgery, Anesthesiology, and Radiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Sharkia 44511, Egypt.ORCID https://orcid.org/0000-0001-8132-9526
Rahul KumarTennessee Department of Agriculture, C. E. Kord Animal Health Diagnostic Laboratory, Nashville, Tennessee 37220, USA.ORCID https://orcid.org/0000-0002-2970-4285
Christiana Rezk Bottros YoussefMicrobiology and Immunology Department, Faculty of Pharmacy, Zagazig University, Zagazig, Sharkia 44519, Egypt.ORCID https://orcid.org/0000-0002-4420-4094
Sagar Mal GoyalVeterinary Population Medicine Department and Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA.ORCID https://orcid.org/0000-0002-7781-3080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine papillomaviruses (BPVs) commonly cause sarcoids in equines worldwide. Equine sarcoids (ESs) reduce the working ability of draft animals and produce untoward cosmetic changes in racing and dancing equine. In this study, nine horses and 16 donkeys with sarcoids were presented to Zagazig University Veterinary Clinic, Zagazig, Egypt. Of these, eight horses and six donkeys were found to be infected with BPV. On sequencing, all 14 viruses were found to be BPV1, which were distributed in two clades without specific differentiation among papillomaviruses (PVs) of donkeys, horses, and cattle. Comparison of 135 aa (319-454) of the sequenced L1 gene with reference strains revealed three conservative mutations (D346N, Q398E, and F441Y) and two nonconservative mutations (T348N and K351T). Illumina sequencing revealed that PVs of donkeys and horses were identical and had 98.5% identity with the closest reference sequence (KX907623) of BPV1. In addition, there was high identity among all genes except E5 and L2. The substitution ranged between 0.5% (nt) and 0.89% (aa) in E4 and 5.18% (nt) and 6.81% (aa) in E5. These results indicate that BPV1 is the main cause of ESs in Egypt without marked phylogenetic variation among PVs of cattle, horses, and donkeys.

Indexed as

Egyptequinepapillomavirusessarcoidwhole genome sequencing

Identifiers

PMID39803352
PMCPMC11724032

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.