Evidence map›Paper›PMID 39803228›Full record

ArticleFood science & nutrition2025

The Effects of Adding Probiotic, Alone and in Combination With Zinc, to Routine Treatment on Recurrence of Hepatic Encephalopathy, Quality of Life, and Sleep Quality in Patients With Cirrhosis: An Open-Label Randomized Controlled Trial.

Leila Amooyi, Leila Alizadeh, Parvin Sarbakhsh, Sara Shojaei-Zarghani, Afshin Gharekhani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leila AmooyiStudent Research Committee, Faculty of Pharmacy Tabriz University of Medical Sciences Tabriz Iran.
Leila AlizadehLiver and Gastrointestinal Diseases Research Center Tabriz University of Medical Sciences Tabriz Iran.
Parvin SarbakhshDepartment of Biostatistics and Epidemiology, Faculty of Health Tabriz University of Medical Sciences Tabriz Iran.
Sara Shojaei-ZarghaniColorectal Research Center Shiraz University of Medical Sciences Shiraz Iran.ORCID https://orcid.org/0000-0001-8479-065X
Afshin GharekhaniDepartment of Clinical Pharmacy (Pharmacotherapy), Drug Applied Research Center Tabriz University of Medical Sciences Tabriz Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Overt hepatic encephalopathy (OHE) is a common complication of decompensated cirrhosis. This study aimed to assess the effects of probiotic, alone and in combination with zinc, on OHE recurrence, Model for End-stage Liver Disease (MELD) score, ammonia level, health-related quality of life (HRQoL), and sleep quality in patients with cirrhosis. We performed an open-label randomized controlled trial on patients with decompensated cirrhosis with a previous history of OHE. Eligible patients (

Indexed as

cirrhosishepatic encephalopathylactuloseprobioticzinc

Identifiers

PMID39803228
PMCPMC11716993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.