ArticleCureus2024
Unravelling the Unseen: A Case Series Exploring the Enigmas of Traumatic Optic Neuropathy.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 authors.
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Abstract
Traumatic optic neuropathy (TON) is a rare condition resulting from damage to the optic nerve due to craniofacial trauma. It can present as direct or indirect injuries, with mechanisms ranging from mechanical disruption by fractures in direct TON to transmitted forces causing shearing and ischemia in indirect TON. These injuries often lead to significant visual impairment or complete vision loss, requiring timely diagnosis and intervention. This case series explores five distinct presentations of TON and its related syndromes: direct TON caused by a displaced optic canal fracture, managed with surgical decompression and corticosteroids; indirect TON associated with orbital fractures, treated with high-dose corticosteroids; a complete optic nerve tear, where surgical intervention was deferred due to irreparable damage; TON complicated by cavernous sinus thrombosis, requiring anticoagulation, antibiotics, and corticosteroids; and traumatic chiasmal syndrome presenting with bitemporal hemianopia, treated with corticosteroids. Advanced imaging modalities, particularly computed tomography (CT) and magnetic resonance imaging (MRI), played a pivotal role in diagnosing the extent and mechanism of injuries, guiding individualized management strategies. Outcomes varied, with partial visual recovery achieved in direct and indirect TON, while cases involving severe structural disruption, such as optic nerve tears and chiasmal injuries, showed minimal or no improvement. The TON case with cavernous sinus thrombosis demonstrated thrombosis resolution but without visual restoration. This series emphasizes the importance of a multidisciplinary and tailored approach, combining advanced imaging and medical or surgical therapies, to optimize outcomes in TON and its variants. However, the limitations of current therapies in cases of severe nerve disruption highlight the critical need for advancements in neuroprotective and regenerative treatments to address this challenging condition.
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