Evidence map›Paper›PMID 39803121›Full record

ArticleCureus2024

NephroCheck as a Predictor of Acute Kidney Injury Following Coronary Artery Bypass Graft Surgery.

Zain Khalpey, Pranav Jutla, Zacharya I Khalpey, Jessa Deckwa, Ujjawal Kumar

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zain KhalpeyDepartment of Cardiothoracic Surgery, HonorHealth, Scottsdale, USA.
Pranav JutlaSchool of Life Sciences, Arizona State University, Tempe, USA.
Zacharya I KhalpeyKhalpey AI Lab, Applied & Translational AI Research Institute (ATARI), Scottsdale, USA.
Jessa DeckwaDepartment of Research, Nihon Kohden Digital Health Solutions, Irvine, USA.
Ujjawal KumarDepartment of Cardiothoracic Surgery, HonorHealth, Scottsdale, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Cardiac surgery-associated acute kidney injury (CSA-AKI) remains a significant complication following coronary artery bypass grafting (CABG), affecting 22%-30% of patients. This study evaluates the efficacy of NephroCheck, a biomarker-based test measuring insulin-like growth factor-binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP2), in predicting postoperative AKI. Methods In this retrospective observational cohort study, 21 patients undergoing isolated CABG were analyzed. NephroCheck values were measured preoperatively, upon ICU admission, and at 24 hours post-admission. Patients with chronic kidney disease (CKD), heart failure, or preoperative serum creatinine of ≥2 mg/dL were excluded. AKI was defined using the Kidney Disease Improving Global Outcomes (KDIGO) criteria through postoperative day 7. Results Seven patients developed postoperative AKI. Preoperative NephroCheck values were significantly elevated in the AKI group compared to controls (1.34 (ng/ml)

Indexed as

acute kidney injurybiomarkerscabgcardiac surgeryigfbp7nephrochecktimp2

Identifiers

PMID39803121
PMCPMC11723713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.