Evidence map›Paper›PMID 39803098›Full record

ArticleCureus2024

Unusual Presentation of Hyperandrogenism in Postmenopausal Women: A Report of Two Patients With Leydig Cell Hyperplasia.

Frederik Duhamel, David Unuane, Stefanie Brock, Stefan Cosyns, Eric Balti

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Frederik DuhamelEndocrine and Diabetes Unit, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.
David UnuaneEndocrine and Diabetes Unit, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.
Stefanie BrockDepartment of Pathology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.
Stefan CosynsDepartment of Gynaecology - Oncology, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.
Eric BaltiEndocrine and Diabetes Unit, Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, BEL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperandrogenism is a highly prevalent and debilitating hormonal disturbance encountered in women presenting with variable phenotypical features. Causes encompass a large spectrum of tumoral and nontumoral etiologies, depending on the patients' age. We report two postmenopausal patients with an unusual etiology of hyperandrogenism. Both underwent salpingo-oophorectomy. While the first patient was cured after bilateral salpingo-oophorectomy, the second patient had residual disease after unilateral surgical management. Complete disease control was achieved after the adjunction of medical treatment. This report emphasizes the indication of bilateral salpingo-oophorectomy for the management of hyperandrogenism in postmenopausal women. A better understanding of the added value of presurgical hormonal status in further characterization of the disease phenotype is needed.

Indexed as

bilateral salpingo-oophorectomyhirsutismhyperandrogenismleydig cell hyperplasiatestosterone

Identifiers

PMID39803098
PMCPMC11725227

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.