Evidence map›Paper›PMID 39802813›Full record

ArticleDental research journal2024

Evaluation of antifungal effect of amphotericin B in comparison with nystatin on Candida species derived from patients undergoing head-and-neck radiotherapy.

Zahra Golestannejad, Zahra Saberi, Mina Jamshidi, Parvin Dehghan, Faezeh Khozeimeh, Elham Faghihian, Nadia Najafizadeh, Mehrnoush Maheronnaghsh, Ahmad Amiri Chermahini

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In one paragraph

Article in Dental research journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zahra GolestannejadDepartment of Oral Medicine, Dental Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Zahra SaberiDepartment of Oral Medicine, Dental Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Mina JamshidiDepartment of Periodontics, Kashan University of Medical Sciences, Kashan, Iran.
Parvin DehghanDepartment of Mycology, Isfahan University of Medical Sciences, Isfahan, Iran.
Faezeh KhozeimehDepartment of Oral Medicine, Dental Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Elham FaghihianDepartment of Oral Medicine, Dental Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Nadia NajafizadehDepartment of Radio Oncology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehrnoush MaheronnaghshDepartment of Mycology, Isfahan University of Medical Sciences, Isfahan, Iran.
Ahmad Amiri ChermahiniDepartment of Endodontics, Kashan University of Medical Sciences, Kashan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is ample evidence showing the development of nystatin-resistant strains in patients undergoing malignancy treatment. Amphotericin B is a polyene antifungal drug that combines with ergosterol to cause cell death and is more effective on fungal species than routine antifungals such as nystatin. This study aimed to compare the effect of nystatin and amphotericin B on fungal species isolated from patients before and during head-and-neck radiotherapy. Materials and Methods: This Results: Before radiotherapy, all albicans strains were sensitive to nystatin, whereas 71.4% were sensitive to amphotericin B. After radiotherapy, Conclusion: The present study showed that before radiotherapy, all species isolated from patients, including

Indexed as

Amphotericin Bantifungal effectnystatinoral candidiasisradiotherapy

Identifiers

PMID39802813
PMCPMC11722741

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.