Evidence map›Paper›PMID 39802811›Full record

ArticleDental research journal2024

Antifungal effect of atorvastatin in comparison with fluconazole on

Zahra Golestannejad, Parvin Dehghan, Nadia Najafizade, Mahnaz Kheirkhah, Maryam Emami Bafrani, Adel Tabesh, Farshad Nadian, Faezeh Khozeimeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dental research journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zahra GolestannejadDepartment of Oral and Maxillofacial Medicine, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Parvin DehghanDepartment of Mycology and Parasitology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Nadia NajafizadeDepartment of Radiation Oncology, Isfahan University of Medical Sciences, Isfahan, Iran.
Mahnaz KheirkhahDepartment of Mycology and Parasitology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Maryam Emami BafraniDental Students' Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Adel TabeshDepartment of Oral and Maxillofacial Medicine, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Farshad NadianDepartment of Prosthodontics, School of Dentistry, Shahre Kord University of Medical Sciences, Shahre Kord, Iran.
Faezeh KhozeimehDepartment of Oral and Maxillofacial Medicine, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head-and-neck radiotherapy can change oral Materials and Methods: In this clinical Results: The results showed that the MIC24, MIC48, and MFC of fluconazole were significantly lower than those of atorvastatin for Conclusion: According to the results, fluconazole has antifungal effects comparable to those of atorvastatin, but in much lower doses. Atorvastatin showed optimal antifungal effects but in doses beyond the clinically applicable threshold.

Indexed as

Atorvastatincandidiasisfluconazolehead-and-neck neoplasmoralradiotherapy

Identifiers

PMID39802811
PMCPMC11722742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.