ReviewToxicology reports2025
Microplastics bioaccumulation in fish: Its potential toxic effects on hematology, immune response, neurotoxicity, oxidative stress, growth, and reproductive dysfunction.
Review in Toxicology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Microplastics and nanoplastics in inflammatory bowel disease: Mechanistic plausibility, human evidence and future research priorities.World journal of gastrointestinal pathophysiology · 2026Review
- Interaction of High-Density Polyethylene Microplastics with Freshwater MicroalgaeInternational journal of molecular sciences · 2026Article
- Dose-dependent acute toxicity of chitosan nanoparticles with dual assessment of multisystem toxicopathology and oxidative stress biomarkers in Nile tilapia.Scientific reports · 2026Article
- Microplastic Exposure Disrupts Energy Homeostasis and Welfare in Goldfish.Animals : an open access journal from MDPI · 2026Article
- Transcriptome and Gene Family Analyses Reveal the Physiological and Immune Regulatory Mechanisms ofAntioxidants (Basel, Switzerland) · 2026Article
- Dietary rayon microfibers differentially reshape rearing water and host associated microbiomes of farmed European sea bass (Dicentrarchus labrax).Environmental microbiome · 2026Article
- Microplastics Induced Dysfunctions in Physiology and Behavior of Fish: A Comprehensive Review.Journal of toxicology · 2026Review
- Plastics as disruptors of feeding, digestive physiology, metabolism, and growth in fish and other aquatic ectothermic vertebrates.Frontiers in endocrinology · 2026Review
- Micro/nanoplastics pollution: emerging challenges for aquatic animals and food crops.Frontiers in toxicology · 2026Review
- Review
- Aquatic Plant Mediates Microplastic Bioavailability in Herbivorous Freshwater Fish.Archives of environmental contamination and toxicology · 2025Article
- Article
- Identification and Characterization of Microplastics in Human Cervicovaginal Lavage Fluids Using Raman Spectroscopy: A Preliminary Study.Life (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
After being exposed, microplastics mostly bioaccumulated in guts and gills of fish, then, through circulation, spread and bioaccumulated in other tissues. Circulatory system of fish is impacted by the microplastic bioaccumulation in their tissues, influencing a number of hematological indices that are connected with immunity, osmotic pressure, blood clotting, molecular transport and fat metabolism. Variables like size, dose, duration, food consumption and species, all affect the bioaccumulation and toxicity of the microplastic, rather than the exposure routes. Microplastics lead to an imbalance in the generation of ROS and antioxidant defense of fish, which resulting in oxidative injury. Moreover, microplastics affect immunological responses through physico-chemical damage, hence produce neurotoxicity and modifies the activity of the acetylcholine esterase. Exposure to microplastics caused damage to the hepatic and gut tissue, affect intestinal barrier function and dysbiosis of microbial composition, altered the metabolism of host, affecting the activities of the digestive enzymes, eventually affecting the growth performance of fish. Microplastics exposure target the HPG axis and interfere with the process of steroidogenesis, apoptosis of the gonadal tissue, ultimately causing reproductive dysfunction. Fish exposed to microplastics have a range of toxic effects
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.