Evidence map›Paper›PMID 39802467›Full record

ArticleRSC advances2025

Apoptotic cell death of stomach cancer lines (AGS) induced by Co-NTB complex through cellular organelles and DNA damage.

Sri Renukadevi Balusamy, Mani Balamurugan, Sumitha Purushothaman, Sivaraman Somasundaram, Mohamed Farouk Elsadek, Daewon Sohn, Saeedah Musaed Almutairi, Ivan Mijakovic, Shadi Rahimi, Haribalan Perumalsamy

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sri Renukadevi BalusamyDepartment of Food Science and Biotechnology, Sejong University Gwangjin-gu Seoul Republic of Korea.
Mani BalamuruganDepartment of Materials Science and Engineering, Seoul National University (SNU) 1 Gwanak ro Seoul 08826 Republic of Korea.ORCID https://orcid.org/0000-0002-9256-6591
Sumitha PurushothamanDepartment of Microbiology, Bioprocess Engineering Division, Smykon Biotech Kanniyakumari India.
Sivaraman SomasundaramDepartment of Chemistry, Saveetha School of Engineering, SIMATS Chennai Tamil Nadu 600124 India.
Mohamed Farouk ElsadekDepartment of Biochemistry, College of Science, King Saud University P.O. 2455 Riyadh 11451 Saudi Arabia.
Daewon SohnDepartment of Chemistry, College of Natural Sciences, Hanyang University Seoul 04763 Republic of Korea.
Saeedah Musaed AlmutairiDepartment of Botany and Microbiology, College of Science, King Saud University P.O. 2455 Riyadh 11451 Saudi Arabia.
Ivan MijakovicSystems and Synthetic Biology Division, Department of Life Sciences, Chalmers University of Technology Gothenburg SE-412 96 Sweden shadir@chalmers.se.
Shadi RahimiSystems and Synthetic Biology Division, Department of Life Sciences, Chalmers University of Technology Gothenburg SE-412 96 Sweden shadir@chalmers.se.ORCID https://orcid.org/0000-0002-8376-9880
Haribalan PerumalsamyResearch Institute for Convergence of Basic Science, Hanyang University Seoul 04763 Republic of Korea harijai2004@gmail.com.ORCID https://orcid.org/0000-0002-6497-5857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given that stomach cancer is the fourth leading cause of cancer-related death, there is a need to develop new drugs. Among various methods, metal-based coordination compounds are considered as an efficient strategy against this type of cancer. Similarly, the benzimidazole moiety plays a crucial role in biology; thus, various benzimidazole-based compounds have been found to be active as potential anticancer drugs and are currently used in clinical trials. In this study, we explored the benzimidazole-based cobalt(ii) complex as an anticancer agent against AGS stomach cancer cell lines. Interestingly, the MTT assay of the Co-NTB complex shows a lower IC

Identifiers

PMID39802467
PMCPMC11711993

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.