Evidence map›Paper›PMID 39802461›Full record

ArticleJVS-vascular insights2024

Challenges and potential solutions to enrollment in a clinical trial of arteriovenous fistula vs arteriovenous graft vascular access strategy.

Matthew P Goldman, Dipal M Patel, Kevin Z Chang, Ross P Davis, Matthew S Edwards, Justin B Hurie, Ashlee Sutsrim, Gabriela Velazquez-Ramirez, Timothy K Williams, Oscar H Grandas and 27 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JVS-vascular insights, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Matthew P GoldmanDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Dipal M PatelDivision of Nephrology, Department of Internal Medicine, Johns Hopkins University, Baltimore.
Kevin Z ChangDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Ross P DavisDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Matthew S EdwardsDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Justin B HurieDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Ashlee SutsrimDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Gabriela Velazquez-RamirezDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Timothy K WilliamsDepartment of Vascular and Endovascular Surgery, Wake Forest University School of Medicine, Winston-Salem.
Oscar H GrandasDepartment of Surgery, University of Tennessee Graduate School of Medicine, Knoxville.
Michael B FreemanDepartment of Surgery, University of Tennessee Graduate School of Medicine, Knoxville.
Michael M McNallyDepartment of Surgery, University of Tennessee Graduate School of Medicine, Knoxville.
Scott L StevensDepartment of Surgery, University of Tennessee Graduate School of Medicine, Knoxville.
Kyla M BennettDivision of Vascular Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison.
Karen WooDivision of Vascular Surgery and Endovascular Therapy, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles.
Christopher G CarstenDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Mark P AndroesDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Joseph-Vincent V BlasDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Brian JonesDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
R Michael PattonDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Rachel ParrDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Sagar S GandhiDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
John W YorkDepartment of Surgery, Division of Vascular Surgery, Prisma Health Upstate, Greenville.
Carlton J YoungDivision of Transplant Surgery, University of Alabama at Birmingham, Birmingham.
Muhammad U RabbaniDivision of Transplant Surgery, University of Alabama at Birmingham, Birmingham.
Ali I GardeziDivision of Nephrology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison.
Lama M AbdelnourDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, University of California, Los Angeles.
Timmy LeeDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham.
Wala M AbusalahDivision of Nephrology, Department of Medicine, University of Tennessee Graduate School of Medicine, Knoxville.
Carlos F ZayasDivision of Nephrology, Department of Medicine, Prisma Health Upstate, Greenville.
Caitlin W HicksDepartment of Surgery, Division of Vascular Surgery and Endovascular Therapy, Johns Hopkins University, Baltimore.
Duvuru GeethaDivision of Nephrology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore.
W Mark BrownDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem.
Haiying ChenDivision of Public Health Sciences, Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem.
Michael AllonDivision of Nephrology, Department of Medicine, University of Alabama at Birmingham.
Mariana MureaDepartment of Internal Medicine, Section on Nephrology, Wake Forest University School of Medicine, Winston-Salem.
AV Access Consortium

Funding

A Randomized Trial of Fistula vs. Graft Arteriovenous Vascular Access in Older Adults with End-Stage Kidney Disease on Hemodialysis: The AV ACCESS TrialR01AG071803 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ALLON, MICHAEL, MUREA, MARIANA · 2021 to 2025
$5.6M
NIA NIH HHS R01 AG071803
6 · The paper itself

Abstract

This article presents the rationale, challenges, and adaptive strategies employed during the initiation and execution of the arteriovenous (AV) access trial-a multicenter randomized controlled trial (RCT) comparing AV fistulas and AV grafts for hemodialysis in older adults with major comorbidities. Motivated by shifts in epidemiologic landscapes and evolving guidelines moving away from a fistula-first approach and to more patient-centric approaches, the objective of this randomized controlled trial was to fill critical knowledge gaps in determining the optimal vascular access for this complex patient population. We outline the challenges encountered in patient recruitment along with measures employed to overcome these obstacles in recruitment. We emphasize the pivotal role of continuous research in overcoming these challenges, underscoring its necessity to achieve a thorough comprehension of optimal vascular access strategies for this complex patient population.

Indexed as

Arteriovenous fistulaArteriovenous graftHemodialysis vascular accessRandomized controlled trial

Identifiers

PMID39802461
PMCPMC11720168

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.