ReviewJournal of molecular and cellular cardiology plus2024
Quest for the ideal assessment of electrical ventricular dyssynchrony in cardiac resynchronization therapy.
Review in Journal of molecular and cellular cardiology plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- In the Search of Noninvasive Methods Delineating Left Bundle Branch Block Amendable With Conduction System Pacing.Pacing and clinical electrophysiology : PACE · 2026Trial
- Implementation of lead V8 as a simple non-invasive tool to improve patient selection in cardiac resynchronization therapy and guide left ventricular lead placement.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Article
- New Pacing Techniques and Non-Invasive Methods That May Improve Response to Cardiac Resynchronization Therapy.Journal of cardiovascular development and disease · 2024Article
- Concepts of Cardiac Dyssynchrony and Dynamic Approach.Diagnostics (Basel, Switzerland) · 2024Review
- Ultra-High-Frequency ECG in Cardiac Pacing and Cardiac Resynchronization Therapy: From Technical Concept to Clinical Application.Journal of cardiovascular development and disease · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper reviews the literature on assessing electrical dyssynchrony for patient selection in cardiac resynchronization therapy (CRT). The guideline-recommended electrocardiographic (ECG) criteria for CRT are QRS duration and morphology, established through inclusion criteria in large CRT trials. However, both QRS duration and LBBB morphology have their shortcomings. Over the past decade, various alternative measures of ventricular dyssynchrony have been proposed, ranging from simple options such as vectorcardiography (VCG), ultra-high frequency ECG, and electrical dyssynchrony mapping to more advanced techniques such as ECG imaging electro-anatomic mapping. Despite promising results, none of these methods have yet been widely adopted in daily clinical practice. The VCG is a relatively cost-effective option for potential clinical implementation, as it can be reconstructed from the standard 12‑lead ECG. With the emergence of conduction system pacing, in addition to predicting the outcome of conventional biventricular CRT, the assessment of electrical dyssynchrony holds promise for defining and optimizing the type of resynchronization strategy. Additionally, artificial intelligence has the potential to reveal unknown features for CRT outcomes, and computer models can provide deeper insights into the underlying mechanisms of these features.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.