Evidence map›Paper›PMID 39802396›Full record

ArticleThe journal of allergy and clinical immunology. Global2025

Nicolau syndrome: A case of ischemic necrosis after subcutaneous immunotherapy.

Joyce Kim, Tim Kaddis, Spencer Boyle, Sandeep Gupta, Vivian Wang, Joseph Yusin

Abstract readCase Reports
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joyce KimDepartment of Medicine, University of California Los Angeles, Los Angeles, Calif.
Tim KaddisDivision of Allergy and Immunology, Greater Los Angeles VA Medical Center, Los Angeles, Calif.
Spencer BoyleDivision of Allergy and Immunology, Greater Los Angeles VA Medical Center, Los Angeles, Calif.
Sandeep GuptaDivision of Allergy and Immunology, Baylor Scott & White Medical Center - Plano, Plano, Tex.
Vivian WangDivision of Allergy and Immunology, Greater Los Angeles VA Medical Center, Los Angeles, Calif.
Joseph YusinDivision of Allergy and Immunology, Greater Los Angeles VA Medical Center, Los Angeles, Calif.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rare injection site reaction known as Nicolau syndrome can occur in patients receiving subcutaneous immunotherapy. This syndrome has been reported only a handful of times in the literature related to subcutaneous immunotherapy.

Indexed as

embolia cutis medicamentosaischemic necrosisNicolau syndromeSubcutaneous immunotherapy

Identifiers

PMID39802396
PMCPMC11719306

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.