ReviewHeliyon2025
Therapeutic potential of seaweeds and their biofabricated nanoparticles in treating urolithiasis: A review.
Review in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urolithiasis affects a significant portion of the global population, causing discomfort and pain. Unfortunately, effective drugs to treat this disorder are currently unavailable due to multiple mechanisms and an incomplete understanding of its causes. Consequently, drugs with multiple targets could be a safer and more effective remedy for treating urolithiasis. Moreover, the current treatment options are expensive and come with a risk of complications and stone recurrence. Therefore, an alternative treatment that can prevent stone recurrence and reduce associated symptoms is necessary. Seaweeds are a rich source of beneficial metabolites, like antioxidants, anti-inflammatory, analgesic, and enzyme-inhibitory properties. Advances in nanotechnology hold great promise for improving the therapeutic potential of these metabolites. However, the use of nanoparticles for treating urolithiasis has yet to be explored well, and only a few reports exist on the use of terrestrial plant-based nanoparticles. This review examines the therapeutic properties of seaweed bioactive compounds and their possible applications in treating urolithiasis. We propose that seaweeds could be an excellent source of essential dietary minerals and other bioactive compounds with multiple targets to treat renal calculus naturally. Additionally, the review highlights the potential of nanomedicine in treating urolithiasis, proposing seaweed-based nanoparticles as a promising treatment option.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.