ArticleInternational journal of general medicine2025
Sex-Specific Analysis of the Relationship Between Ventricular Premature Contractions Frequency Distribution and Heart Rate: A Cross-Sectional Study in Chinese Adults.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Premature ventricular complexes increase with heart rate in patients with mitral valve prolapse.International journal of cardiology. Heart & vasculature · 2026Article
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4 authors.
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Abstract
Objective: To investigate the correlation between premature ventricular contraction (PVC) frequency and heart rate (HR) in Chinese adults, with an emphasis on sex-specific differences in clinical characteristics. Patients and Methods: This retrospective study analyzed 24-hour Holter monitoring data from 478 inpatients at the First People's Hospital of Yibin between January 2021 and December 2022. The inclusion criteria were age ≥18 years, ≥20 hours of Holter recording, frequent PVCs (≥ 500 PVCs), and complete clinical profiles. Patients were stratified into three groups on the basis of the hourly correlation between PVC counts and HR: fast heart rate-related PVC (F-HR-PVC), slow heart rate-related PVC (S-HR-PVC), and independent heart rate-related PVC (I-HR-PVC). Heart rate variability (HRV) indices were assessed to evaluate autonomic nervous system activity. Results: Among the 478 patients, 267 were males and 211 were females with a mean age of 65.7±13.0 years. The mean PVC burden was 5.7±7.0%, and the mean left ventricular ejection fraction (LVEF) was 59.1±8.7%. In males, the F-HR-PVC group was most common (45.3%), while in females, the I-HR-PVC group was most prevalent (50.2%). Despite these observed differences, a chi-square test did not reveal statistically significant differences in the distribution of VPC profiles between sexes (P=0.167). Analysis of clinical characteristics and Holter indices across sex groups showed significant differences in males, particularly in age, maximum heart rate, and minimum heart rate (P < 0.05). In females, significant intergroup differences were observed in VPC burden (P < 0.05). Conclusion: Although no significant sex differences were observed in the correlation between PVC frequency and HR, the study suggests a potential gender influence on VPC characteristics. These findings may inform future research and have implications for the development of sex-specific diagnostic and therapeutic strategies for PVCs.
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