Evidence map›Paper›PMID 39801679›Full record

ArticleJournal of clinical and translational science2025

Informing a sinusitis clinical trial protocol: A focus group study with clinicians and staff.

Ruey-Ying Liu, Charles Fencil, Tom Whitfield, Daniel Merenstein, Bruce Barrett, David Rabago, Alex H Krist, Sebastian T Tong, Aleksandra E Zgierska, Derjung M Tarn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical and translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruey-Ying LiuDepartment of Sociology, National Chengchi University, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-2770-2147
Charles FencilDepartment of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, VA, USA.
Tom WhitfieldMedStar Health Research Institute, Washington, DC, USA.
Daniel MerensteinDepartment of Family Medicine, Georgetown University Medical Center, Washington, DC, USA.
Bruce BarrettDepartment of Family Medicine and Community Health, University of Wisconsin-Madison, Madison, WI, USA.
David RabagoDepartment of Family and Community Medicine, The Pennsylvania State University, Hershey, PA, USA.
Alex H KristDepartment of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-4060-9155
Sebastian T TongDepartment of Family Medicine, University of Washington, Seattle, WA, USA.
Aleksandra E ZgierskaDepartment of Family and Community Medicine, The Pennsylvania State University, Hershey, PA, USA.
Derjung M TarnDepartment of Family Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates practicing clinician and staff perspectives on potential protocol modifications for the "Nasal Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis" (NOSES) study, a pragmatic randomized controlled trial aiming at improving acute rhinosinusitis management. Focus groups with clinicians and staff at the pretrial stage recommended expanding participant age inclusion criteria, incorporating patients with COVID-19, and shortening the supportive care phase. Participants also discussed patient engagement and recruitment strategies. These practical insights contribute to optimizing the NOSES trial design and underscore the value of qualitative inquiries and healthcare stakeholder engagement in informing clinical trial design.

Indexed as

acute rhinosinusitisfocus grouppragmatic clinical trialqualitative methodstakeholder engagement

Identifiers

PMID39801679
PMCPMC11713428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.