Evidence map›Paper›PMID 39801568›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Real-World Treatment Outcomes of an Artificial Tear Containing Arabinogalactan, Hyaluronic Acid and Trehalose Among Subjects with Dry Eye.

Andrea Bedei, Pedro Rocha Cabrera, Luis Oliveira, Laura Castellini, Giulia De Grazia, Stefano Remiddi

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea BedeiOphthalmology Department Casa di Cura San Camillo, Forte dei Marmi, Italy.
Pedro Rocha CabreraOphthalmology Department Hospital San Juan de Dios Tenerife, Santa Cruz de Tenerife, Spain.
Luis OliveiraOphthalmology Department Hospital Santo Antonio, Porto, Portugal.ORCID 0000-0001-7532-5991
Laura CastelliniOphthalmology Department Casa di Cura San Camillo, Forte dei Marmi, Italy.ORCID 0009-0001-4555-0861
Giulia De GraziaDepartment of Research and Development, MD Italy, Albano Laziale, Italy.
Stefano RemiddiDepartment of Research and Development, MD Italy, Albano Laziale, Italy.ORCID 0009-0004-7795-6016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To assess the efficacy, adherence, and tolerability of a new artificial tear based on arabinogalactan, hyaluronic acid, and trehalose in a population with dry eye disease (DED). Methods: A retrospective, real-world, post-marketing study identified 96 adult patients (aged 18-80 years) with signs and symptoms of dry eye. These patients received fixed combination therapy with eye drops containing arabinogalactan, hyaluronic acid, and trehalose at various dosing schedules. The data for this study were collected from April 2022 to June 2023. Patients underwent evaluation at baseline (T0) and after a follow-up period of two-three months (T1) using a patient-reported questionnaire. Results: In 96 adult patients (71 women and 25 men) with dry eye due to various conditions, the results indicated a 98% positive response to therapy. This response included improvements in vision (13%), comfort (39%), redness (13%), itching (16%), photophobia (4%), and tearing (14%). Additionally, 61% of the patients experienced 1-2 hours of comfort following instillation. Conclusion: This real-life post-marketing study demonstrated clinical improvement of signs and symptoms in patients with dry eye disease using a new artificial tear medical device based on arabinogalactan, hyaluronic acid, and trehalose.

Indexed as

arabinogalactandry eyehyaluronic acidpost-marketing studyreal-world studytrehalose

Identifiers

PMID39801568
PMCPMC11724676

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