Evidence map›Paper›PMID 39801518›Full record

ArticleResearch square2025

Immune targets for schistosomiasis control identified by a genome-wide association study of African snail vectors.

Michelle Steinauer, Tom Pennance, Jacob Tennessen, Johannie Spaan, Tammie McQuistan, George Ogara, Fredrick Rawago, Kennedy Andiego, Boaz Mulonga, Meredith Odhiambo and 4 more

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Michelle SteinauerWestern University of Health Sciences.ORCID 0000-0002-3745-2401
Tom PennanceWestern University of Health Sciences.
Jacob TennessenHarvard University.
Johannie SpaanWestern University of Health Sciences.
Tammie McQuistanWestern University of Health Sciences.
George OgaraKenya Medical Research Institute.
Fredrick RawagoKenya Medical Research Institute.
Kennedy AndiegoKenya Medical Research Institute.
Boaz MulongaKenya Medical Research Institute.
Meredith OdhiamboKenya Medical Research Institute.
Martin MutukuKenya Medical Research Institute.
Gerald MkojiKenya Medical Research Institute (KEMRI).
Eric LokerUniversity of New Mexico.
Maurice OdiereKenya Medical Research Institute.ORCID 0000-0001-7561-4873

Funding

Snail-Related Studies of Transmission & Control of Schistosomiasis in KenyaR37AI101438 · NIAID · UNIVERSITY OF NEW MEXICO · PI ERIC SAMUEL LOKER · 2017 to 2026
$3.7M
Identifying schistosomiasis resistance genes of snail vectors in hotspot transmission zones: Translating from laboratory models to the field.R01AI141862 · NIAID · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI STEINAUER, MICHELLE L. · 2019 to 2023
$1.7M
NIAID NIH HHS R01 AI141862NIAID NIH HHS R37 AI101438
6 · The paper itself

Abstract

Schistosomiasis, a neglected tropical disease, is transmitted by freshwater snails. Interruption of transmission will require novel vector-focused interventions. We performed a genome-wide association study of African snails,

Identifiers

PMID39801518
PMCPMC11722531

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.