Evidence map›Paper›PMID 39801454›Full record

ArticleJournal of cardiovascular electrophysiology2025

The Prevalence and Predictors of Atrioventricular Blocks in Syrian Patients Reporting to the Emergency Department During the Ongoing Conflict: A Cross-Sectional Study.

Ibrahim Antoun, Alkassem Alkhayer, Aref Jalal Eldin, Alamer Alkhayer, Khaled Yazji, Riyaz Somani, G André Ng, Mustafa Zakkar

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Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Ibrahim AntounFaculty of Medicine, University of Aleppo, Aleppo, Syria.
Alkassem AlkhayerDepartment of Medicine, University of Tishreen's Hospital, Latakia, Syria.
Aref Jalal EldinDepartment of Medicine, University of Tishreen's Hospital, Latakia, Syria.
Alamer AlkhayerDepartment of Medicine, University of Tishreen's Hospital, Latakia, Syria.
Khaled YazjiDepartment of Cardiology, The View Hospital, Qatar, Qatar.
Riyaz SomaniDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
G André NgDepartment of Cardiovascular Sciences, University of Leicester, Leicester, UK.
Mustafa ZakkarFaculty of Medicine, University of Damascus, Damascus, Syria.

Funding

GAN is supported by British Heart Foundation Research Excellence Award (RE/24/130031), British Heart Foundation Programme (Grant RG/17/3/32774), Medical Research Council Biomedical Catalyst Developmental Pathway Funding Scheme (MR/S037306/1) and NIHR i4i (Grant NIHR204553).
6 · The paper itself

Abstract

backgroundAtrioventricular block (AVB) is a cardiac conduction disorder that can lead to significant clinical outcomes, particularly in resource-limited and conflict-affected regions. In Syria, healthcare infrastructure has been severely impacted by ongoing conflict, potentially affecting the prevalence and management of AVB.

methodsWe conducted a cross-sectional study at Tishreen University Hospital in Latakia, Syria, with patients > 40 who presented to the emergency department (ED) from June 1 to August 1, 2024. Routine 12-lead ECGs were performed, with AVB diagnoses confirmed by two independent cardiology consultants. Exclusion criteria included pre-existing AVB, pacemaker presence, hemodynamic instability, and ECG diagnostic discrepancies. Patient demographics and comorbidities were assessed, and logistic regression analyses identified predictors of AVB.

resultsThe final analysis included 692 patients, of which AVB was detected in 7% of the cohort. Patients with AVB were significantly older (median age 76 vs. 54 years, p < 0.001) and had higher rates of ischemic heart disease (IHD) (62% vs. 14%, p < 0.001) and diabetes (56% vs. 21%, p = 0.01). Logistic regression showed older age (odds ratio [OR]: 2.8, 95% confidence interval [CI]: 1.6-5.6, p < 0.001), IHD (OR: 1.9, 95% CI: 1.4-4.5, p < 0.001), and DM (OR: 3.9, 95% CI: 2.9-8.3, p < 0.001) were independently associated with AVB.

conclusionAVB prevalence in the Syrian ED setting is high, with age, IHD, and diabetes as significant predictors. Routine ECG screening in EDs may facilitate early AVB detection in at-risk populations, especially in conflict-affected regions with limited healthcare resources. This approach could improve outcomes by enabling timely intervention in high-risk patients.

Indexed as

Atrioventricular BlockEmergency Service, HospitalAdultAgedAged, 80 and overComorbidityCross-Sectional StudiesElectrocardiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsPrevalenceRisk AssessmentRisk FactorsconflictECGheart blockscreeningSyria

Identifiers

PMID39801454
PMCPMC11903377

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.