Evidence map›Paper›PMID 39801408›Full record

ReviewActas espanolas de psiquiatria2025

Alcohol Use Disorders and Suicidal Behaviour: A Narrative Review.

Matteo Lupi, Stefania Chiappini, Alessio Mosca, Andrea Miuli, Ilenia Di Muzio, Carlotta Marrangone, Tommaso Piro, Francesco Semeraro, Mirko Alfonsi, Livia Miotti and 6 more

Abstract readReview
In one paragraph

Review in Actas espanolas de psiquiatria, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Matteo LupiNHS, Mental Health Department, Psychiatric Service of Diagnosis and Treatment, "Madonna del Soccorso" Hospital, AST Ascoli Piceno, 63074 San Benedetto del Tronto, Italy.
Stefania ChiappiniUniCamillus International Medical University, 00131 Rome, Italy.
Alessio MoscaDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Andrea MiuliDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Ilenia Di MuzioDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Carlotta MarrangoneDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Tommaso PiroDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Francesco SemeraroDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.
Mirko AlfonsiUnit of Clinical Psychiatry, Department of Clinical Neurosciences/DIMSC, School of Medicine, Polytechnic University of Marche, 60121 Ancona, Italy.
Livia MiottiCatholic University of the Sacred Heart, 00168 Rome, Italy.
Maria CarlucciStudi Cognitivi, Cognitive Psychotherapy School and Research Center, 63074 San Benedetto del Tronto, Italy.
Alessandro CaranoNHS, Mental Health Department, Psychiatric Service of Diagnosis and Treatment, "Madonna del Soccorso" Hospital, AST Ascoli Piceno, 63074 San Benedetto del Tronto, Italy.
Gilberto Di PettaNHS, Mental Health Department, Psychiatric Service of Diagnosis and Treatment, Santa Maria delle Grazie Hospital, ASL 2, 80134 Naples, Italy.
Domenico De BerardisNHS, Head of Mental Health Department, ASL Teramo, 64100 Teramo, Italy.
Umberto VolpeUnit of Clinical Psychiatry, Department of Clinical Neurosciences/DIMSC, School of Medicine, Polytechnic University of Marche, 60121 Ancona, Italy.
Giovanni MartinottiDepartment of Neuroscience, Imaging and Clinical Sciences, University "G. d'Annunzio", 66013 Chieti-Pescara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlcohol Use Disorders (AUD), affective disorders, and personality disorders are among the most prevalent mental health conditions observed in individuals exhibiting suicidal behavior, encompassing both completed and attempted suicides. A robust association between AUD and suicidal behavior has been established through retrospective and prospective cohort studies. Research on the relationship between alcohol consumption and self-harm has predominantly focused on Western and high-income countries, whereas approximately one-third of the global population, including half of the world's countries, lacks accessible suicide data. This study aims to present an updated review of empirical evidence regarding the risk of suicide associated with AUD in both developed and developing nations.

methodsWe identified published meta-analyses, reviews, systematic reviews, randomized controlled trials, clinical studies, clinical trials, controlled clinical trials, observational studies, and case reports written in English and published between January 2004 and June 2024. Our search yielded a total of 312 papers. After reviewing titles and abstracts, 232 articles were excluded from the initial records. Following full-text review of the remaining 80 articles, a qualitative synthesis was conducted, highlighting the most representative 41 papers for inclusion in this overview.

resultsOur analysis indicates that alcohol abuse is a significant risk factor for all forms of suicidal behavior. Alcohol consumption functions as both a predisposing and precipitating factor, contributing to maladaptive behaviors in both developing and developed countries. The clinical condition is exacerbated by alcohol use, which in turn increases the risk of suicide.

conclusionsFurther research is essential to develop targeted psychological and pharmacological interventions aimed at preventing and treating these conditions, with the goal of reducing the risk of suicidal behavior associated with AUD. In developing countries, integrating public health and clinical strategies is crucial for effectively addressing suicide prevention.

Indexed as

AlcoholismAlcohol-Related DisordersSuicideSuicide, AttemptedDeveloped CountriesDeveloping CountriesHumansRisk Factors

Identifiers

PMID39801408
PMCPMC11726211

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.