Evidence map›Paper›PMID 39801119›Full record

ArticleGlobal spine journal2025

Prevention and Management of Posterior Wound Complications Following Oncologic Spine Surgery: Narrative Review of Available Evidence and Proposed Clinical Decision-Making Algorithm.

Owen P Leary, Aayush Setty, Jung Ho Gong, Rohaid Ali, Jared S Fridley, Charles G Fisher, Arjun Sahgal, Laurence D Rhines, Jeremy J Reynolds, Áron Lazáry and 13 more

Erratum issuedAbstract read
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In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Plastic and reconstructive surgery in spinal sarcoma resection: a review of indications, techniques, and outcomes.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Owen P LearyDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0002-6282-828X
Aayush SettyDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Jung Ho GongDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.ORCID 0000-0003-0382-8279
Rohaid AliDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Jared S FridleyDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Charles G FisherCombined Neurosurgical and Orthopaedic Spine Program, University of British Columbia, Vancouver, BC, Canada.
Arjun SahgalDepartment of Radiation Oncology, Sunnybrook Hospital, University of Toronto, Toronto, ON, Canada.
Laurence D RhinesDepartment of Neurosurgery, M.D. Anderson Cancer Center, Houston, TX, USA.
Jeremy J ReynoldsOxford Spinal Surgery Unit, Oxford University Hospitals, Oxford, UK.
Áron LazáryNational Center for Spinal Disorders, Buda Health Center, Budapest, Hungary.ORCID 0000-0002-0157-719X
Ilya LauferDepartment of Neurosurgery, New York University Grossman School of Medicine, New York, NY, USA.
Alessandro GasbarriniIstituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
Nicolas DeaCombined Neurosurgical and Orthopaedic Spine Program, University of British Columbia, Vancouver, BC, Canada.
Jorrit-Jan VerlaanDepartment of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands.
Chetan BettegowdaDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Stefano BorianiIstituto Ortopedico Rizzoli, University of Bologna, Bologna, Italy.
Addisu MesfinDepartment of Orthopaedic Surgery, Medstar Orthopaedic Institute, Georgetown University School of Medicine, Washington, DC, USA.ORCID 0000-0003-0076-4185
Alessandro LuzzatiSant'Ambrogio Hospital, IRCCS Galeazzi, Milan, Italy.
John H ShinDepartment of Neurosurgery, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA.
Riccardo CecchinatoSant'Ambrogio Hospital, IRCCS Galeazzi, Milan, Italy.
Francis J HornicekDepartment of Orthopaedics, University of Miami Miller School of Medicine, Miami, FL, USA.
Matthew L GoodwinDepartment of Orthopaedic Surgery, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
Ziya L GokaslanDepartment of Neurosurgery, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designNarrative Review.

objectiveContextualized by a narrative review of recent literature, we propose a wound complication prevention and management algorithm for spinal oncology patients. We highlight available strategies and motivate future research to identify optimal and individualized wound management for this population.

methodsWe conducted a search of recent studies (2010-2022) using relevant keywords to identify primary literature in support of current strategies for wound complication prevention and management following spine tumor surgery. When primary literature specific to spine tumor cases was not available, data were extrapolated from studies of other spine surgery populations. Results were compiled into a proposed clinical algorithm to guide practice considering available evidence.

resultsBased on available literature, we recommend individualized stratification of patients according to identifiable risk factors for wound complication and propose several interventions which might be employed preventatively, including intrawound antibiotic administration, negative pressure wound therapy, and primary flap closure of the surgical wound. Of these, the available evidence, weighing possible risks vs benefits, most strongly favors primary flap closure of surgical wounds, particularly for patients with multiple risk factors. A secondary algorithm to guide management of wound complications is also proposed.

conclusionsWound complications such as SSI and dehiscence remain a significant source of morbidity following spine tumor surgery. Triaging patients on an individualized basis according to risk factors for complication may aid in selecting appropriate prophylactic strategies to prevent these complications. Future research in this area is still needed to strengthen recommendations.

Indexed as

clinical algorithmspinal oncologyspine surgerysurgical site infectionwound dehiscence

Identifiers

PMID39801119
PMCPMC11726526

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.