Evidence map›Paper›PMID 39801115›Full record

ArticleGlobal spine journal2025

Role of Posterior Carbon Fiber Implants in Spine Tumor Surgery.

Christopher A Alvarez-Breckenridge, Robert North, Claudio Tatsui, Naresh Kumar, Sheng-Fu Lo, Karim Mohammed, Jeremy Reynolds, Aron Lazary, Ilya Laufer, Jorrit Jan Verlaan and 11 more

Abstract read
In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Christopher A Alvarez-BreckenridgeDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-5997-6532
Robert NorthDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Claudio TatsuiDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Naresh KumarDepartment of Orthopaedic Surgery, National University Health System, Singapore, Singapore.
Sheng-Fu LoDepartment of Neurosurgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, USA.
Karim MohammedDepartment of Orthopedics, Mayo Clinic, Rochester, MN, USA.
Jeremy ReynoldsDepartment of Spinal Division, Oxford University Hospitals NHS Trust, Oxford, UK.ORCID 0000-0002-1632-139X
Aron LazaryDepartment of Spine Surgery, Semmelweis University, Budapest, Hungary.ORCID 0000-0002-0157-719X
Ilya LauferDepartment of Neurosurgery, NYU Langone Medical Center, New York, NY, USA.
Jorrit Jan VerlaanDepartment of Orthopaedics, UMC Utrecht, Utrecht, Netherlands.
Ziya GokaslanDepartment of Spine, Brown University, Providence, RI, USA.
Alessandro LuzzatiDepartment of Orthopedics, IRCCS Galeazzi Orthopaedic Institute, Milan, Italy.
Riccardo CecchinatoDepartment of Orthopedics, IRCCS Galeazzi Orthopaedic Institute, Milan, Italy.
John ShinDepartment of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA.
Francis HornicekDepartment of Orthopaedics, University of Miami Miller School of Medicine, Miami, FL, USA.
Alexander DischDepartment of Orthopedics, Medical University at Dresden, Dresden, Germany.ORCID 0000-0001-8414-4041
Matthew GoodwinDepartment of Orthopaedic Surgery, Washington University, St. Louis, MO, USA.
Rory GoodwinDepartment of Neurosurgery, Duke University Hospital, Durham, NC, USA.ORCID 0000-0002-6540-2751
Arjun SahgalDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, ON, CA.
Alessandro GasbarriniDepartment of Spine Surgery, Institutio Ortopedico Rizzoli di Bolgna, Bologna, Italy.
Stefano BorianiDepartment of Orthopedics, IRCCS Galeazzi Orthopaedic Institute, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designNarrative Review.

objectiveThe management of spinal tumors requires a multi-disciplinary approach including surgery, radiation, and systemic therapy. Surgical approaches typically require posterior segmental instrumentation to maintain long-term spinal stability. Carbon fiber reinforced pedicle screws (CFRP) are increasingly used in the oncologic setting due to reductions in both imaging artifacts and radiotherapy perturbations compared to titanium implants. We performed a review of the literature and highlight advantages and future areas of study for CFRP.

methodsWe performed a systematic review of the literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and identified 10 articles including 573 patients. Across all studies we reviewed patient demographics, tumor types treated, hardware-related features, complication rates, recurrence, survival, and follow-up.

resultsAcross 10 studies, a total of 1371 screws placed. Surgical and non-surgical complications were reported in 18.3% of patients. Disease progression at the surgical site was detected in 7.3% of patients. There was no significant difference in clinical or hardware complications between CFRP or titanium implants. The most frequent complication attributable to implanted CFRP hardware included screw breakage in 2.4% and loosening in 1.7% of patients, respectively.

conclusionCFRP provide a unique tool in the setting of spinal oncology. With a safety profile comparable to titanium, we review the documented advantages of CFRP posterior implants compared to titanium, while also addressing their current limitations. Additionally, we highlight several areas of future research to identify the optimal patients who will achieve the greatest benefit of CFRP.

Indexed as

carbon fiberpedicle screwtumor

Identifiers

PMID39801115
PMCPMC11726513

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.