Evidence map›Paper›PMID 39800829›Full record

SynthesisSchizophrenia bulletin2025

The Prevalence of Attention Deficit Hyperactivity Disorder in Psychotic Disorders: Systematic Review and Meta-analysis.

Nicholas Cheng, Shayden Bryce, Michael Takagi, Allie Pert, Audrey Rattray, Evangeline Fisher, Marcus Lai, Mia Geljic, Sarah Youn, Stephen J Wood and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Australian and New Zealand journal of psychiatry · 2026
    Guideline
  2. Review
  3. Article
  4. Article
  5. Maternal immune activation in mice recapitulates features of attention-deficit/hyperactivity disorder (ADHD) in susceptible offspring.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nicholas ChengTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria 3168, Australia.ORCID 0000-0003-2209-4717
Shayden BryceOrygen, Parkville, Victoria 3052, Australia.
Michael TakagiTurner Institute for Brain and Mental Health, Monash University, Clayton, Victoria 3168, Australia.
Allie PertOrygen, Parkville, Victoria 3052, Australia.
Audrey RattrayOrygen, Parkville, Victoria 3052, Australia.
Evangeline FisherOrygen, Parkville, Victoria 3052, Australia.
Marcus LaiSchool of Psychological Sciences, The University of Melbourne, Parkville, Victoria 3004, Australia.
Mia GeljicOrygen, Parkville, Victoria 3052, Australia.
Sarah YounOrygen, Parkville, Victoria 3052, Australia.ORCID 0000-0002-6477-2806
Stephen J WoodOrygen, Parkville, Victoria 3052, Australia.
Kelly AllottOrygen, Parkville, Victoria 3052, Australia.ORCID 0000-0002-0640-4634

Funding

Monash UniversityUniversity of Melbourne
6 · The paper itself

Abstract

backgroundAlthough attention deficit hyperactivity disorder (ADHD) is known to be common in psychotic disorders, reported prevalence rates vary widely, with limited understanding of how different factors (eg, assessment methods, geographical region) may be associated with this variation. The aim was to conduct a systematic review and meta-analysis to determine the prevalence of ADHD in psychotic disorders and factors associated with the variability in reported rates. STUDY

designSearches were conducted in MEDLINE, Embase, PsycINFO, CINAHL, and Scopus in May 2023. Studies were eligible if the frequency of ADHD was reported in psychotic disorder samples. Pooled prevalence meta-analyses were performed. Subgroup analyses and meta-regressions explored whether demographic and study characteristics were associated with reported rates. STUDY

resultsThirty-six studies were included, involving 30 726 individuals. The pooled lifetime prevalence of ADHD in psychotic disorders was 18.49% (95% CI 11.78%, 27.83%). The between-study heterogeneity was high (I2 = 98.4% [95% CI 98.2%, 98.6%]). Subgroup analyses revealed higher prevalence rates when using ADHD DSM-IV criteria compared to International Classification of Diseases (ICD)-10. Rates in childhood-onset psychotic disorders were higher than adolescent- and adult-onset psychotic disorder samples. Rates were higher in North America compared to other regions. Meta-regressions indicated a decrease in prevalence rates with publication year.

conclusionsThe prevalence of ADHD in psychotic disorders appears higher than in the general population, highlighting the need for clinical attention and further research into this comorbidity. Reported rates, however, vary significantly. Reasons may include diagnostic criteria, age of psychosis onset, region, study design, and publication year. Future research should investigate these factors using rigorous ADHD assessment protocols.

Indexed as

Attention Deficit Disorder with HyperactivityPsychotic DisordersComorbidityHumansPrevalenceattention deficit disordercomorbidityneurodevelopmental disorderspsychosisschizophrenia

Identifiers

PMID39800829
PMCPMC12599807

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.