Evidence map›Paper›PMID 39800754›Full record

ArticleBMC research notes2025

Prevalence of depressive symptom and its associated factors among epilepsy patients in Amhara region, Ethiopia: cross-sectional study.

Sintayehu Simie Tsega, Yilkal Abebaw Wassie, Alebachew Ferede Zegeye, Mekdes Kiflu, Sisay Maru Wubante, Kennean Mekonnen, Birhaneslasie Gebeyehu Yazew, Birye Dessalegn Mekonnen, Yeshambel Andargie Tarekegn

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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4citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Sintayehu Simie TsegaDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia. simies952@gmail.com.
Yilkal Abebaw WassieDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Alebachew Ferede ZegeyeDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Mekdes KifluDepartment of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.
Sisay Maru WubanteDepartment of Health Informatics, Institute of Public Health, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Kennean MekonnenDepartment of Emergency and critical care, School of nursing, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.
Birhaneslasie Gebeyehu YazewDepartment of Nursing, College of Medicine and Health Sciences, Injibara University, Injibara, Ethiopia.
Birye Dessalegn MekonnenAmhara Public Health Institute, Bahir Dar, Ethiopia.
Yeshambel Andargie TarekegnDepartment of Otorhinolaryngology (ENT), School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepressive symptom is the most common type of psychiatric co-morbidity among persons with epilepsy. Epilepsy patients are identified as at higher risk of suffering depressive symptom explicitly in low- and middle-income countries due to poor mental health care systems and financial burdens. The co-occurrence of depressive symptom among epilepsy patients deteriorates the prognosis of the disease and diminishes the quality of life of both the patients and their families. However, there is limited evidence on the prevalence of depressive symptom and associated factors in Ethiopia. Therefore, this study is intended to assess the prevalence of depressive symptom and associated factors among epilepsy patients attending in Amhara region, Ethiopia.

methodA multi-center institution-based cross-sectional study was done among epilepsy patients attending at Amhara region, Ethiopia. The Hospital Anxiety Depression tool was used to assess depressive symptom. To determine the factors associated with depressive symptom, a binary logistic regression model was used. Adjusted Odds Ratio (AOR) with the 95% Confidence Interval (CI) was reported in the multivariable binary logistic regression analysis.

resultsAbout 406 participants were registered in the study with a response rate of 97.6%. The prevalence of depressive symptom among epilepsy patients was 53.9% [95%CI: 49.1%, 58.8%]. In the multivariable binary logistic regression analysis, taking polytherapy treatment [AOR = 1.87, 95% CI: 1.04, 3.36], perceived stigma [AOR = 5.73, 95%CI: 3.11, 10.55], poor antiepileptic medication adherence [AOR = 3.33, 95%CI: 1.30, 8.54] and having poor [AOR = 5.83, 95%CI: 2.44, 13.90] and moderate social support [AOR = 3.08, 95%CI: 1.34, 7.09] were significantly associated with depressive symptom.

conclusionsThis study revealed that the magnitude of depressive symptom among epilepsy patients in Ethiopia was relatively high and multiple factors determined the likelihood of depressive symptom. Thus, healthcare providers and concerned stakeholders should strengthen comprehensive health education to reduce the magnitude and consequences of depressive symptom among this segment of the population. Moreover, strong social support with special attention should be given to epilepsy patients.

Indexed as

DepressionEpilepsyAdolescentAdultComorbidityCross-Sectional StudiesEthiopiaFemaleHumansMaleMiddle AgedPrevalenceQuality of LifeRisk FactorsYoung AdultAmhara regionAssociated factorsDepressive symptomEpilepsy

Identifiers

PMID39800754
PMCPMC11725183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.