Evidence map›Paper›PMID 39800744›Full record

ArticleMolecular psychiatry2025

Anorexia nervosa is associated with higher brain mu-opioid receptor availability.

Kyoungjune Pak, Jouni Tuisku, Henry K Karlsson, Jussi Hirvonen, Eleni Rebelos, Laura Pekkarinen, Lihua Sun, Aino Latva-Rasku, Semi Helin, Johan Rajander and 3 more

Abstract read
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In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Questioning the validity of food addiction: a critical review.Frontiers in behavioral neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kyoungjune PakDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea. ilikechopin@me.com.ORCID 0000-0001-5051-1894
Jouni TuiskuTurku PET Centre, University of Turku, Turku, Finland.
Henry K KarlssonTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-6734-7891
Jussi HirvonenTurku PET Centre, University of Turku, Turku, Finland.
Eleni RebelosTurku PET Centre, University of Turku, Turku, Finland.
Laura PekkarinenTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0002-5596-0485
Lihua SunTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0002-9931-9497
Aino Latva-RaskuTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-8786-9160
Semi HelinTurku PET Centre, University of Turku, Turku, Finland.
Johan RajanderTurku PET Centre, Accelerator Laboratory, Åbo Akademi University, Turku, Finland.
Max KarukiviTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0002-8478-3051
Pirjo NuutilaTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0001-9597-338X
Lauri NummenmaaTurku PET Centre, University of Turku, Turku, Finland.ORCID 0000-0002-2497-9757

Funding

National Research Foundation of Korea (NRF) 2020R1F1A1054201
6 · The paper itself

Abstract

Anorexia nervosa (AN) is a severe psychiatric disorder, characterized by restricted eating, fear to gain weight, and a distorted body image. Mu-opioid receptor (MOR) functions as a part of complex opioid system and supports both homeostatic and hedonic control of eating behavior. Thirteen patients with AN and thirteen healthy controls (HC) were included in this study. We measured (1) MOR availability with [

Indexed as

Anorexia NervosaBrainReceptors, Opioid, muAdolescentAdultFemaleFentanylFluorodeoxyglucose F18GlucoseHumansMagnetic Resonance ImagingMaleNucleus AccumbensPositron-Emission TomographyYoung AdultcarfentanilFentanylFluorodeoxyglucose F18GlucoseReceptors, Opioid, mu

Identifiers

PMID39800744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.