Evidence map›Paper›PMID 39800366›Full record

ArticleInternational wound journal2025

Frailty and comorbidity in older adults with and without diabetes and chronic leg ulcer: A cross-sectional study.

Burcu Duluklu, John Ivory, Aideen McElvaney, Angela Bligh, Marion Cahill-Collins, Georgina Gethin, Aaron Liew, Duygu Sezgin

Abstract read
In one paragraph

Article in International wound journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Burcu DulukluFaculty of Nursing, Hacettepe University, Ankara, Turkiye.ORCID https://orcid.org/0000-0002-6955-2538
John IvorySchool of Nursing and Midwifery, University of Galway, Galway, Ireland.ORCID https://orcid.org/0000-0002-8445-4602
Aideen McElvaneySchool of Nursing and Midwifery, University of Galway, Galway, Ireland.
Angela BlighSchool of Nursing and Midwifery, University of Galway, Galway, Ireland.
Marion Cahill-CollinsAlliance for Research and Innovation in Wounds, University of Galway, Galway, Ireland.
Georgina GethinSchool of Nursing and Midwifery, University of Galway, Galway, Ireland.
Aaron LiewSchool of Medicine, University of Galway, Galway, Ireland.
Duygu SezginSchool of Nursing and Midwifery, University of Galway, Galway, Ireland.

Funding

College of Medicine, Nursing and Health Sciences, University of GalwayEuropean Wound Management Association (EWMA)
6 · The paper itself

Abstract

This descriptive, cross-sectional study aimed to identify whether having a chronic leg ulcer (CLU), in addition to diabetes, contributed to frailty in individuals ≥65 years old. It also explored the associations between frailty, pre-frailty and other factors. 125 participants aged ≥65 attending outpatient clinics in Ireland were categorised into three groups: (1) diabetes-only and no CLU, (2) CLU-only and no diabetes, and (3) diabetes and CLU. Frailty status was identified using the Groningen Frailty Indicator (GFI) and the Physical Frailty Phenotype (PFP). The mean age was 76.09 ± 7.31. Overall, 90 (72%) had diabetes, and 89 (71.2%) had CLU in the past 6 months. While 124 (99.2%) were frail according to the GFI, 122 (97.6%) were either physically frail (n = 40, 32%) or pre-frail (n = 82, 65.6%) based on the PFP. There was no difference between the three groups regarding general frailty status (p > 0.05). However, being aged ≥75, having CLU and having CLU in addition to diabetes were associated with frailty severity (p < 0.05). Slow gait, inability to go to the toilet and dress/undress independently were the common factors contributing to frailty. Age, comorbidities and CLU were associated with frailty severity. Incorporating multidimensional frailty screening into regular clinic visits for older adults with CLU is recommended.

Indexed as

Diabetes MellitusFrail ElderlyFrailtyLeg UlcerAgedAged, 80 and overChronic DiseaseComorbidityCross-Sectional StudiesFemaleGeriatric AssessmentHumansIrelandMalechronic leg ulcerscomorbiditiesdiabetesfrailtypre‐frailty

Identifiers

PMID39800366
PMCPMC11725367

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.