Evidence map›Paper›PMID 39800307›Full record

ArticleThe Journal of biological chemistry2025

A leucine responsive small RNA AbcR200 regulates expression of the lactate utilization (lut) operon in Acinetobacter baumannii DS002.

Harshita Nagasai Yakkala, Ashok Kumar Madikonda, Sandhya Rani Behera, Vijaykumar Pillalamarri, Kashif Gulam Mohammad, Ganeshwari Dhurve, Prasad Tammineni, Suresh Babu Pakala, Dayananda Siddavattam

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Article in The Journal of biological chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Harshita Nagasai YakkalaDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Ashok Kumar MadikondaDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Sandhya Rani BeheraDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Vijaykumar PillalamarriDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Kashif Gulam MohammadDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Ganeshwari DhurveDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Prasad TammineniDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Suresh Babu PakalaDepartment of Biochemistry, School of Life Sciences, University of Hyderabad, Hyderabad, India.
Dayananda SiddavattamDepartment of Animal Biology, School of Life Sciences, University of Hyderabad, Hyderabad, India. Electronic address: sdsl@uohyd.ac.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Noncoding small RNAs are essential for modulating bacterial gene expression, especially under carbon and nutrient-limited conditions. In this study, by using both in silico and molecular hybridization tools, we identified a carbon source responsive small RNA in Acinetobacter baumannii DS002. Expression of corresponding gene, abcR200, located at the intergenic region of omt (O-methyl transferase) and orf72 genes, is under the transcriptional control of a global transcriptional factor, leucine responsive regulatory protein (Lrp). A sequence motif that serves as a target for Lrp was found overlapping the abcR200 promoter (P

Indexed as

Acinetobacter baumanniiBacterial ProteinsGene Expression Regulation, BacterialLactic AcidLeucineLeucine-Responsive Regulatory ProteinOperonRNA, BacterialRNA, Small UntranslatedPromoter Regions, GeneticBacterial ProteinsLactic AcidLeucineLeucine-Responsive Regulatory ProteinRNA, BacterialRNA, Small Untranslatedbacterial small RNAsgene expressionlactate utilizationleucine responsive regulatory proteinpost transcriptional regulation

Identifiers

PMID39800307
PMCPMC11869524

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.