Evidence map›Paper›PMID 39799338›Full record

ArticleBMC nephrology2025

Risk factors for radial artery calcification in patients with and without uremia.

Jian-Bing Hao, Si-Yu Wang, Tong Chen, Bo Yuan, Li-Rong Hao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jian-Bing HaoDepartment of Nephrology, Southern University of Science and Technology Hospital, Shenzhen, China. haojianbing@sustech-hospital.com.
Si-Yu WangDepartment of Nephrology, Southern University of Science and Technology Hospital, Shenzhen, China.
Tong ChenDepartment of Nephrology, Southern University of Science and Technology Hospital, Shenzhen, China.
Bo YuanDepartment of Clinical Laboratory, Southern University of Science and Technology Hospital, Shenzhen, China.
Li-Rong HaoDepartment of Nephrology, Southern University of Science and Technology Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCalcification of the radial artery is one of the main causes of anastomotic stenosis in autogenous arteriovenous fistulas in uremic patients. However, the pathogenesis of calcification is still unknown. This study attempted to screen and validate the risk factors for vascular calcification in patients with uremia.

methodsSerum of blood were collected and tissue samples from radial artery were obtained from 60 uremia patients with or without hemodialysis. General biochemical indicators and calcification-related molecules were collected and detected via ELISA or correlation analysis. In addition, pathological changes and calcification-related molecules in the radial artery were evaluated by HE or immunohistochemical staining.

resultsThere were differences in total calcium, calcium-phosphorus products, allograft inflammatory factor 1 (AIF-1), intact parathyroid hormone (iPTH), vitamin D (VD), fibroblast growth factor 23 (FGF23) and soluble klotho (sKlotho) in the blood of uremic patients with or without hemodialysis. Furthermore, these factors are related to calcification of the radial artery. The expression of AIF-1, PTHR1, VDR, FGF23 and sKlotho was also increased in the calcified radial artery.

conclusionsThe levels of AIF-1, PTH, VDR, FGF23 and sKlotho in serum were associated with calcification of the radial artery in patients with uremia. Furthermore, calcification of the radial artery was further aggravated by abnormalities in calcium and phosphorus in maintenance hemodialysis patients.

Indexed as

Radial ArteryUremiaVascular CalcificationAdultAgedCalciumCalcium-Binding ProteinsDNA-Binding ProteinsFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseHumansKlotho ProteinsMaleMicrofilament ProteinsAIF1 protein, humanCalciumCalcium-Binding ProteinsDNA-Binding ProteinsFGF23 protein, humanFibroblast Growth Factor-23Fibroblast Growth FactorsGlucuronidaseKlotho ProteinsKL protein, humanMicrofilament ProteinsParathyroid HormoneReceptors, CalcitriolVDR protein, humanVitamin DAllograft inflammatory factor 1Parathyroid hormoneRadial artery calcificationUremiaVitamin D

Identifiers

PMID39799338
PMCPMC11724451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.