Evidence map›Paper›PMID 39799131›Full record

ArticleScientific reports2025

Passion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells.

Haruka Uozumi, Shinpei Kawakami, Yuko Matsui, Sadao Mori, Akira Sato

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Haruka UozumiDepartment of Biochemistry and Molecular Biology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan.
Shinpei KawakamiResearch and Development Institute, Health Science Research Center, Morinaga & Co., Ltd, Yokohama, Kanagawa, Japan.
Yuko MatsuiResearch and Development Institute, Health Science Research Center, Morinaga & Co., Ltd, Yokohama, Kanagawa, Japan.
Sadao MoriResearch and Development Institute, Health Science Research Center, Morinaga & Co., Ltd, Yokohama, Kanagawa, Japan.
Akira SatoDepartment of Biochemistry and Molecular Biology, Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan. akirasat@rs.tus.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a major cause of vision loss among adults. We investigated the protective effects of passion fruit seed extract (PFSE) and its rich polyphenol piceatannol in an AMD cell model in which human retinal pigment epithelial ARPE-19 cells were exposed to hydrogen peroxide (H

Indexed as

Hydrogen PeroxidePassifloraPlant ExtractsRetinal Pigment EpitheliumSeedsAdenosine TriphosphateCell LineCell SurvivalGlycolysisHumansMitochondriaOxidative StressProtective AgentsStilbenes3,3',4,5'-tetrahydroxystilbeneAdenosine TriphosphateHydrogen PeroxidePlant ExtractsProtective AgentsStilbenesAge-related macular degenerationARPE-19 cellsFunctional foodHydrogen peroxideMitochondrial functionOxidative stressPassion fruit seed extractPiceatannol

Identifiers

PMID39799131
PMCPMC11724910

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.