Evidence map›Paper›PMID 39798095›Full record

ArticleSTAR protocols2025

Protocol to study neuronal membrane proteasome function in mouse peripheral sensory neurons.

Emily R Krueger, Taylor R Church, Anna Brennan, Fulya Türker, Eric Villalón Landeros

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in STAR protocols, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emily R KruegerDepartment of Molecular Pharmacology and Neuroscience, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA.
Taylor R ChurchDepartment of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Anna BrennanDepartment of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Fulya TürkerDepartment of Molecular Biology and Genetics, Faculty of Science, İhsan Doğramacı Bilkent University, Ankara 06800, Turkey.
Eric Villalón LanderosDepartment of Molecular Pharmacology and Neuroscience, Loyola University Chicago Stritch School of Medicine, Maywood, IL 60153, USA; Center for Translational Research and Education, Health Sciences Campus, 2160 South First Avenue, Maywood, IL 60153, USA. Electronic address: evillalon@luc.edu.

Funding

The Role of the Neuronal Membrane Proteasome in the Peripheral Nervous System and Pain SensationF31NS134239 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Taylor Renne Church · 2023 to 2026
$196k
NINDS NIH HHS F31 NS134239
6 · The paper itself

Abstract

Neuronal membrane proteasomes (NMPs) are expressed on a subset of somatosensory dorsal root ganglion (DRG) neurons and influence mechanical and pain sensitivity. Here, we present a protocol for studying NMP function in mouse peripheral sensory neurons. We describe steps for procuring and culturing primary DRG neurons. We then detail biochemical and antibody feeding approaches to analyze NMP expression and localization. Finally, we include Ca

Indexed as

Cell MembraneProteasome Endopeptidase ComplexSensory Receptor CellsAnimalsCalciumCells, CulturedGanglia, SpinalMiceCalciumProteasome Endopeptidase ComplexAntibodyCell cultureNeuroscienceProtein expression and purification

Identifiers

PMID39798095
PMCPMC11969408

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.