Evidence map›Paper›PMID 39798051›Full record

SynthesisJournal of ultrasound2025

Effectiveness of prenatal ultrasound in fetal sex identification: a systematic review and meta-analysis.

Eunice Amankona, Andrew Donkor, Benedict Apaw Agyei, Ijeoma Anyitey-Kokor, Alexander Tawiah Odoi, Yaw Amo Wiafe

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of ultrasound, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eunice AmankonaDepartment of Medical Imaging, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Andrew DonkorDepartment of Medical Imaging, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Benedict Apaw AgyeiDepartment of Medical Imaging, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ijeoma Anyitey-KokorDepartment of Medical Imaging, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Alexander Tawiah OdoiDepartment of Obstetrics and Gynaecology, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Yaw Amo WiafeDepartment of Medical Imaging, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. wadart1@gmail.com.ORCID http://orcid.org/0000-0002-0944-0577

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review and meta-analysis aimed to assess the accuracy and success rate of ultrasound in determining fetal sex. A search was conducted on Medline, Cochrane Library, and EMBASE databases, and the reference lists of selected studies were also reviewed. Meta-analyses were performed using Revman 5.4.1 and Meta-DiSc 2.0. Twenty-eight studies met the criteria for inclusion in the systematic review. Nine studies reported the accuracy rate of first-trimester fetal sex identification, with a mean accuracy of 85% and a median of 87%. Six studies provided accuracy rates for second and third-trimester identifications, with mean and median rates of 92% and 99%, respectively. A pooled sensitivity and specificity analysis shows that the sensitivity increased from 69% at 11 weeks to 89% at 12 weeks to 96% at 13 weeks. Forest plots on the success rates indicated no significant statistical differences between first-trimester ultrasound sex determination and actual birth sex, with p values of 0.06 for males and 0.08 for females. Similarly, second and third-trimester forest plots showed p values of 0.70 for males and 0.14 for females. In conclusion, ultrasound accuracy for fetal sex determination rises from 87% in first to 99% in second trimesters. The success rate shows no significant difference for either trimester. However, male sex is more easily detected in the second and third trimesters, while female sex is more easily detected in the first trimester. The sensitivity of fetal sex detection in the first trimester increases with gestational age. These findings suggest that prenatal ultrasound sex determination can be useful in managing sex-related pregnancy complications.

Indexed as

Sex Determination AnalysisUltrasonography, PrenatalFemaleHumansMalePregnancyPregnancy Trimester, FirstSensitivity and SpecificityAngle of genital tubercleAnogenital distanceDeterminationFetal sexSagittal signUltrasound

Identifiers

PMID39798051
PMCPMC12496360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.