Evidence map›Paper›PMID 39798047›Full record

SynthesisInternational urology and nephrology2025

Partial versus radical cystectomy in localized colorectal cancer: a systematic review and meta-analysis.

Bernardo Fontel Pompeu, Lucas Soares de Souza Pinto Guedes, Carlos Magno Costa Coaracy Sobrinho, Julia Hoici Brunini, Leonardo Borges, Sergio Mazzola Poli de Figueiredo, Samuel Aguiar Junior, Fernanda Bellotti Formiga

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bernardo Fontel PompeuDepartment of Colorectal Surgery, Heliopolis Hospital, São Paulo, SP, Brazil. bernardo.pompeu@online.uscs.edu.br.ORCID http://orcid.org/0009-0009-2960-3810
Lucas Soares de Souza Pinto GuedesUniversity of São Caetano do Sul, Rua Santo Antônio, 50-Centro, São Caetano do Sul, SP, 09521-160, Brazil.ORCID http://orcid.org/0009-0008-8437-9682
Carlos Magno Costa Coaracy SobrinhoDepartment of Colorectal Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0005-5897-7660
Julia Hoici BruniniDepartment of Colorectal Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0009-0001-9321-2330
Leonardo BorgesDepartment of Urology, Albert Einstein Hospital, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-4009-7428
Sergio Mazzola Poli de FigueiredoDepartment of Surgery, University of North Carolina, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-2986-8164
Samuel Aguiar JuniorDepartment of Colorectal Tumors, A.C. Camargo Cancer Center, São Paulo, Brazil.ORCID http://orcid.org/0000-0003-3476-727X
Fernanda Bellotti FormigaDepartment of Colorectal Surgery, Heliopolis Hospital, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-7225-7145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLocally advanced colorectal tumors frequently invade adjacent organs, particularly the urinary bladder in the sigmoid colon and upper rectum, complicating multivisceral resections. This study compared postoperative outcomes of partial cystectomy (PC) and total cystectomy (TC) in patients with locally advanced colorectal cancer.

methodsA systematic review was conducted in PubMed, Scopus, Central Register of Clinical Trials, and Web of Science for studies published up to November 2024. Odds ratios (ORs) and mean differences (MDs) with 95% confidence intervals (CIs) were pooled using a random-effects model. Heterogeneity was assessed with I

resultsNine retrospective studies including 894 patients were analyzed. Among them, 433 (48.43%) underwent PC, and 461 (51.57%) underwent TC. Compared to TC, PC was associated with significantly lower rates of surgical site infection (OR 0.33; 95% CI 0.13-0.80; p = 0.015), shorter operative time (MD - 169.7 min; 95% CI - 214.1 to - 125.3; p < 0.01), reduced blood loss (MD - 1005.9 ml; 95% CI - 1362.1 to - 649.8; p < 0.01), and shorter hospital stay (MD - 6.6 days; 95% CI - 9.4 to - 3.9; p < 0.01). No significant differences were observed between groups in local or distant recurrence, urinary and intestinal leaks, pelvic abscess, ileus, urinary tract infection, or 90-day mortality.

conclusionPartial cystectomy demonstrated superior postoperative outcomes, including fewer surgical site infections, reduced operative time, less blood loss, and shorter hospitalization. Oncological outcomes and other postoperative complications were comparable between PC and TC, supporting PC as a safe and effective option in selected patients.

Indexed as

Colorectal NeoplasmsCystectomyHumansPostoperative ComplicationsTreatment OutcomeAdvanced colorectal cancerCystectomyNeobladderUrostomy

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.