ArticleAnnals of medicine2025
Impact of time from blood specimens collection to centrifugation on the diagnosis of gestational diabetes mellitus.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Letter to the editor regarding to 'impact of time from blood specimens collection to centrifugation on the diagnosis of gestational diabetes mellitus'.Annals of medicine · 2026Article
- Response to letter regarding 'impact of time from blood specimens collection to centrifugation on the diagnosis of gestational diabetes mellitus'.Annals of medicine · 2026Article
- Fasting Metabolite Panel for OGTT-Free Diagnosis of Gestational Diabetes Mellitus: A Machine Learning Approach Validated in Dual Cohorts.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
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Authors and funding
11 authors.
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Abstract
objectiveThe process of glycolysis from blood collection to centrifugation impacts the diagnosis of gestational diabetes mellitus (GDM). However, the specific characteristics of the working environment in China and its influence on GDM diagnosis still need to be clarified.
methodsFirstly, 15 pregnant women were recruited, and six specimens were collected from each in a fasting state. The specimens were left at room temperature for different times (0.5, 1, 2, 3, 4, and 5 h) and then centrifuged. Subsequently, data were collected from pregnant women who underwent oral glucose tolerance test (OGTT) between June 1, 2021, and July 30, 2022. Pregnant women were categorized into different groups based on different pre-treatment times, and the incidence of GDM was calculated for each group.
resultsGlucose levels gradually decreased as the specimen remained longer before centrifugation, a decrease of 1.15 mmol/L (27.58%) from the initial glucose level (3.02 ± 0.30 mmol/L
conclusionsIn the Chinese healthcare environment, prolonging specimen pre-treatment time can affect GDM diagnosis. Therefore, standardizing specimen pre-treatment is crucial to minimize potential effects.
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