Evidence map›Paper›PMID 39797404›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2025

REM obstructive sleep apnea: prevalence and clinical associations in a high-altitude population.

Diego Fernando Severiche Bueno, Ana María Gonzalez, Diana Paola Rivera-Leon, María Teresa Vargas Cuervo, Janeth Marcela Mateus-Palacios, Juanita Agudelo-Agudelo, Diana Paola Casas, Luisa Fernanda Enciso-B, Nadia Juliana Proaños, Federico Fernández-Bernal and 3 more

Abstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Sleep studies: does the altitude matter?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Article
  2. REM-related obstructive sleep apnea: is it still an enigma or do we even care?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Diego Fernando Severiche BuenoFundación Neumológica Colombiana, Bogotá, Colombia.
Ana María GonzalezFundación Neumológica Colombiana, Bogotá, Colombia.
Diana Paola Rivera-LeonFundación Neumológica Colombiana, Bogotá, Colombia.
María Teresa Vargas CuervoFundación Neumológica Colombiana, Bogotá, Colombia.
Janeth Marcela Mateus-PalaciosFundación Neumológica Colombiana, Bogotá, Colombia.
Juanita Agudelo-AgudeloFundación Neumológica Colombiana, Bogotá, Colombia.
Diana Paola CasasFundación Neumológica Colombiana, Bogotá, Colombia.
Luisa Fernanda Enciso-BFundación Neumológica Colombiana, Bogotá, Colombia.
Nadia Juliana ProañosFundación Neumológica Colombiana, Bogotá, Colombia.
Federico Fernández-BernalFundación Neumológica Colombiana, Bogotá, Colombia.
Elida Dueñas MezaFundación Neumológica Colombiana, Bogotá, Colombia.
Mauricio GonzalezFundación Neumológica Colombiana, Bogotá, Colombia.
María Angelica Bazurto ZapataFundación Neumológica Colombiana, Bogotá, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesRapid eye movement (REM)-associated obstructive sleep apnea (OSA) (REM OSA) has a prevalence of 17-74% of all OSA cases. At high altitude and in Latin America, there are no data on REM OSA and its relationship to daytime sleepiness and comorbidities. This study aimed to determine the prevalence of REM OSA and the differences in clinical and polysomnographic characteristics between OSA and REM OSA in a population living at 2,640 meters.

methodsA retrospective cross-sectional study was conducted on adults in Bogotá, Colombia between January and December 2022. Patients were considered to have REM OSA if they had a REM sleep duration of at least 30 minutes and the ratio of REM-apnea-hypopnea index to non-REM-apnea-hypopnea index was > 2, and non-REM-apnea-hypopnea index < 15. For comparing the OSA and OSA REM groups, the χ

resultsPatients with REM OSA and mild OSA had more severe nocturnal desaturation indices compared to mild non-REM OSA. Patients with OSA had a higher prevalence of arterial hypertension and ischemic heart disease.

conclusionsREM OSA prevalence in a population living at high altitude was low compared with other studies. The patients with REM OSA and mild OSA had more severe nocturnal desaturation indexes compared to REM OSA at sea level. This study suggests a possible subgroup of patients with mild OSA at high altitude who may benefit from a discussion about initiating continuous positive airway pressure therapy. CITATION: Severiche Bueno DF, Gonzalez AM, Rivera-Leon DP, et al. REM obstructive sleep apnea: prevalence and clinical associations in a high-altitude population.

Indexed as

AltitudeSleep Apnea, ObstructiveSleep, REMAdultColombiaCross-Sectional StudiesFemaleHumansMaleMiddle AgedPolysomnographyPrevalenceRetrospective Studiescardiovascular diseasedaytime sleepinesshigh altitudeobstructive sleep apneaprevalenceREM sleepsystemic arterial hypertension

Identifiers

PMID39797404
PMCPMC12048312

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.