Evidence map›Paper›PMID 39797278›Full record

ReviewJournal of clinical medicine2025

From Symptoms to Satisfaction: Optimizing Patient-Centered Care in Dry Eye Disease.

Edoardo Villani, Stefano Barabino, Giuseppe Giannaccare, Antonio Di Zazzo, Pasquale Aragona, Maurizio Rolando

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Imaging Approaches for the Diagnosis of Dry Eye: A Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edoardo VillaniDepartment of Clinical Sciences and Community Health, University of Milan, Eye Clinic San Giuseppe Hospital, IRCCS Multimedica, 20123 Milan, Italy.ORCID 0000-0003-3811-5893
Stefano BarabinoOcular Surface & Dry Eye Center, ASST Fatebenefratelli SACCO, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-6317-8848
Giuseppe GiannaccareEye Clinic, Department of Surgical Sciences, University of Cagliari, 09123 Cagliari, Italy.ORCID 0000-0003-2617-0289
Antonio Di ZazzoOphthalmology Operative Complex Unit, University Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-5264-5973
Pasquale AragonaOphthalmology Clinic, Department of Biomedical Sciences, University of Messina, 98100 Messina, Italy.
Maurizio RolandoOcular Surface Unit, ISPRE Ophthalmics, 16129 Genoa, Italy.ORCID 0000-0002-4982-1462

Funding

Thea Unnumbered
6 · The paper itself

Abstract

Dry eye disease (DED) is a multifactorial, chronic, and often relapsing condition with a significant impact on patient quality of life (QoL). Symptoms such as ocular discomfort and visual disturbances are diverse and frequently misaligned with objective clinical signs, complicating diagnosis and management. DED not only interferes with daily activities like reading, driving, and computer use but also imposes a substantial economic burden due to direct healthcare costs and reduced work productivity. Beyond its ocular manifestations, DED has been associated with higher prevalence rates of depression and anxiety, with a complex bidirectional relationship. Patients with DED may experience psychological distress that exacerbates symptoms, leading to a vicious cycle that further impairs QoL. This underscores the importance of integrating mental health screening into the management of DED, particularly for high-risk populations. Optimizing the care of DED patients requires empathy, effective communication, and the establishment of a therapeutic alliance that acknowledges patient experiences and involves them in personalized treatment plans. Such an approach can improve patient satisfaction, enhance treatment adherence, and address both ocular and psychological dimensions of the disease. This paper highlights current evidence on the impact of DED symptoms and its association with mental health and recommends strategies to improve clinical management through a patient-centered approach.

Indexed as

depressiondry eye diseasemental healthocular surfacePROMsquality of lifesatisfactionsymptomstear filmtherapeutic alliance

Identifiers

PMID39797278
PMCPMC11721487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.