An Optical Wireless Communication System for Physiological Data Transmission in Small Animals.

In biomedical research, telemetry is used to take automated physiological measurements wirelessly from animals, as it reduces their stress and allows recordings for large data collection over long periods. The ability to transmit high-throughput data from an in-body device (e.g., implantable systems, endoscopic capsules) to external devices can also be achieved by radiofrequency (RF), a standard wireless communication procedure. However, wireless in-body RF devices do not exceed a transmission speed of 2 Mbit/s, as signal absorption increases dramatically with tissue thickness and at higher frequencies. This paper presents the design of an optical wireless communication system (OWCS) for neural probes with an optical transmitter, sending out physiological data through an optical signal that is detected by an optical receiver. The optical receiver position is controlled by a tracking system of the small animal position, based on a cage with a piezoelectric floor. To validate the concept, an OWCS based on a wavelength of 850 nm for a data transfer of 5 Mbit/s, with an optical power of 55 mW, was demonstrated for a tissue thickness of approximately 10 mm, measured in an optical tissue phantom.