Evidence map›Paper›PMID 39796715›Full record

ArticleCancers2024

RadiOnCOVID: Multicentric Analysis of the Impact of COVID-19 on Patients Undergoing Radiation Therapy in Italy.

Andrea Emanuele Guerini, Giulia Marvaso, Sandro Tonoli, Giulia Corrao, Maria Ausilia Teriaca, Matteo Sepulcri, Melissa Scricciolo, Alessandro Gava, Sabrina Montrone, Niccolò Giaj-Levra and 11 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The landscape of definitive radiotherapy discontinuation: a 5-year institutional audit and clinical profiling.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Andrea Emanuele GueriniDepartment of Radiation Oncology, Istituto del Radio O. Alberti, Spedali Civili Hospital, Piazzale Spedali Civili 1, 25121 Brescia, Italy.
Giulia MarvasoDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5339-8038
Sandro TonoliUOC Radioterapia e Medicina Nucleare, ASST di Cremona, 26100 Cremona, Italy.ORCID 0000-0003-4060-7029
Giulia CorraoDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-5757-6073
Maria Ausilia TeriacaRadiotherapy and Radiosurgery Department, Humanitas Research Hospital, 20089 Rozzano, Italy.
Matteo SepulcriRadiotherapy, Veneto Institute of Oncology, IOV-IRCCS Padua, 35128 Padova, Italy.ORCID 0000-0002-9654-5587
Melissa ScriccioloRadiation Oncology Division, Clinical Oncology Department, Ospedale dell'Angelo, 30174 Venice, Italy.ORCID 0000-0002-0112-9215
Alessandro GavaDepartment of Radiation Oncology, Azienda Ospedaliera ULSS 9, 31100 Treviso, Italy.
Sabrina MontroneU.O. Radioterapia, Azienda Ospedaliero-Universitaria Pisana, Via Roma 69, 56120 Pisa, Italy.
Niccolò Giaj-LevraDipartimento di Radioterapia Oncologica Avanzata, IRCCS Sacro Cuore Don Calabria Hospital, Via Don Angelo Sempreboni, 37124 Negrar di Valpolicella, Italy.ORCID 0000-0002-4328-0319
Barbara Noris ChiordaDepartment of Radiation Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.
Giovanna MantelloSOD Radioterapia (Dipartimento Medicina Interna), Azienda Ospedaliero Universitaria delle Marche, 60002 Ancona, Italy.ORCID 0000-0001-9314-6006
Francesco FioricaDipartimento di Oncologia Clinica, AULSS 9 Scaligera, 37122 Verona, Italy.ORCID 0000-0002-9404-3655
Simona BorghesiRadiation Oncology Unit of Arezzo-Valdarno, Azienda USL Toscana Sud Est, 52100 Arezzo, Italy.
Liliana BelgioiaU.O. Radioterapia Oncologica, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0003-0508-6344
Angela CaroliSOC Oncologia Radioterapica, Centro di Riferimento Oncologico, Istituto di Ricovero e Cura a Carattere Scientifico, 33081 Aviano, Italy.ORCID 0000-0002-9968-7679
Alba FiorentinoDepartment of Medicine and Surgery, LUM University, 70010 Casamassima, Italy.ORCID 0000-0003-4201-5852
Radioncovid Study Group
Barbara Alicja Jereczek-FossaDivision of Radiation Oncology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-8151-3673
Stefano Maria MagriniDepartment of Radiation Oncology, Istituto del Radio O. Alberti, Spedali Civili Hospital, Piazzale Spedali Civili 1, 25121 Brescia, Italy.ORCID 0000-0002-4126-733X
Michela BuglioneDepartment of Radiation Oncology, Istituto del Radio O. Alberti, Spedali Civili Hospital, Piazzale Spedali Civili 1, 25121 Brescia, Italy.ORCID 0000-0002-5485-1260

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methods and materialsPatients with ongoing or planned anticancer treatment at 19 Italian Radiation Oncology centers were included in the study retrospectively from 3 February 2020 to 31 December 2020 and prospectively from 1 January 2021 to 31 May 2021. Anonymized data were processed through a specific website and database. Antineoplastic treatment characteristics and timing and outcomes of COVID-19 and its impact on radiotherapy or systemic therapy were described.

resultsThe retrieved cohort included 41,039 patients that received treatment or were planned for therapy in the study period. Overall, 123 patients had a confirmed COVID-19 diagnosis during antineoplastic treatment (group A) and 99 patients before treatment start (group B). The incidence of COVID-19 across the whole cohort in the index period was 0.54% (groups A + B) and 0.30% considering only group A. A total of 60 patients developed severe COVID-19, and a total of 45 patients died as a consequence of the infection (incidence of 0.15% and 0.11%, respectively). Nonetheless, mortality among COVID-19 patients was high, with an attributable death rate after confirmed infection of 20.27%. Among the 123 patients in group A, 37.4% required temporary treatment suspension, 32.5% definitive suspension and 37 patients continued treatment while positive. As for the 99 patients in group B, 53.5% experienced temporary delay, 20.2% experienced definitive treatment suspension and 26.3% had no delay.

conclusionsMost of the patients with a COVID-19 diagnosis in our cohort recovered and completed their treatment; nonetheless, the attributable death rate after confirmed infection was 20.27%, and mortality was high among cancer patients with severe COVID-19 presentation. The global incidence of death due to COVID-19 or severe COVID-19 was low and decreased over time. Radiation oncology activity could be safely continued during the COVID-19 pandemic with the adoption of adequate preventive measures.

Indexed as

coronavirusCOVID-19radiation therapyradiotherapy

Identifiers

PMID39796715
PMCPMC11720150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.