Evidence map›Paper›PMID 39796592›Full record

ArticleNutrients2024

Association Between Serum Folate Concentrations and 10-Year Stroke Risk in a Prospective Community Cohort: Mediation and Interaction Analyses.

Zhe Liang, Fangfang Fan, Bo Liu, Kaiyin Li, Hongyu Chen, Jia Jia, Yong Huo, Jianping Li, Yan Zhang

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhe LiangDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.ORCID 0000-0002-9311-4431
Fangfang FanDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.ORCID 0000-0001-8351-4821
Bo LiuDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.ORCID 0000-0002-3676-4999
Kaiyin LiDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Hongyu ChenDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Jia JiaDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Yong HuoDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.
Jianping LiDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.ORCID 0000-0002-8526-1095
Yan ZhangDepartment of Cardiology, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China.ORCID 0000-0002-7508-4160

Funding

National High Level Hospital Clinical Research Funding (High Quality Clinical Research Project of Peking University First Hospital) 2022CR71National Key Research and Development Program of China 2021YFC2500503National Natural Science Foundation of China 81703288National Natural Science Foundation of China 82170452NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory PeptidesState Key Laboratory of Vascular Homeostasis and Remodeling, Peking University
6 · The paper itself

Abstract

The relationship between folate concentrations and stroke risk remains unestablished, and the mediation effect of homocysteine (Hcy) and interaction effect of methylenetetrahydrofolate reductase (

Indexed as

Folic AcidMethylenetetrahydrofolate Reductase (NADPH2)StrokeAgedChinaFemaleGenotypeHomocysteineHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsFolic AcidHomocysteineMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humancohort studyepidemiologyfolatehomocysteineMTHFR C677T gene polymorphismstroke

Identifiers

PMID39796592
PMCPMC11722758

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.