Evidence map›Paper›PMID 39796591›Full record

Trial reportNutrients2024

Chronobiological Factors Influencing Glycemic Control and Birth Outcomes in Gestational Diabetes Mellitus.

Amalia Messika, Yoel Toledano, Eran Hadar, Riva Tauman, Oren Froy, Raanan Shamir

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02916667 (Chrono Nutrition Intervention Program in Gestational Diabetes Mellitus), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02916667 naunknown statusnot on this map

Chrono Nutrition Intervention Program in Gestational Diabetes Mellitus

TypeinterventionalSponsorRabin Medical CenterRan2016 to 2018Enrolled280ConditionsGDMArmsdietary guidelines
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Observational
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amalia MessikaHelen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva 4941492, Israel.
Yoel ToledanoHelen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva 4941492, Israel.
Eran HadarHelen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva 4941492, Israel.
Riva TaumanFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Oren FroyInstitute of Biochemistry, Food Science and Nutrition, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 7610001, Israel.ORCID 0000-0001-9061-3780
Raanan ShamirFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.ORCID 0000-0002-4287-3681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesStudies have shown that chronobiological factors may adversely affect glycemic control in patients with type 2 diabetes mellitus. We assessed the association of chronobiological factors with glycemic control and neonatal birth weight in women with GDM.

methodsA prospective cohort study included 208 women aged 18-45 years with a singleton pregnancy who were randomly selected from among women undergoing follow-up for GDM at the Maternal-Fetal Medicine Unit of a tertiary medical center. Nutrition, sleep, and lifestyle patterns were assessed from onset of GDM until birth along with glycemic control and birth outcomes.

resultsMultivariate analyses on a cohort of 208 women revealed that suboptimal glycemic control was associated with a late breakfast (RR = 2.26; 95% CI 1.09-4.67), increased carbohydrate intake in the evening (RR = 1.19; 95% CI 1.003-1.42), and poor sleep quality (RR = 2.14; 95% CI 1.04-4.41). The adjusted relative risk for neonatal birth weight above the 85th percentile was associated with increased carbohydrate intake in the morning (RR = 1.70; 95% CI 1.30-2.23) and increased carbohydrate intake in the evening (RR = 1.39; 95% CI 1.16-1.67).

conclusionsChronobiological factors are associated with suboptimal glycemic control and birth weight above the 85th percentile in women with GDM. The study was registered under ClinicalTrials.gov.org, identifier: NCT02916667.

Indexed as

Birth WeightBlood GlucoseDiabetes, GestationalGlycemic ControlAdolescentAdultCircadian RhythmDietary CarbohydratesFemaleHumansInfant, NewbornLife StyleMiddle AgedPregnancyPregnancy OutcomeProspective StudiesBlood GlucoseDietary Carbohydratesbirth weight percentilechronobiological disorderschrono-nutritiongestational diabetes mellitusglycemic control

Identifiers

PMID39796591
PMCPMC11722567

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.