Evidence map›Paper›PMID 39796564›Full record

ArticleNutrients2024

Infant Passive Protection Against Coronavirus Through Exclusive Breastfeeding: A Cross-Sectional Study.

Yasmin Amaral, Antonio Egidio Nardi, Daniele Marano, Ana Carolina Carioca da Costa, Maria Elisabeth Moreira

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Short-lived neutralizing activity against SARS-CoV-2 in newborns of immunized mothers.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yasmin AmaralPostdoctoral Program-Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), Rio de Janeiro 21941-909, Brazil.ORCID 0000-0001-8159-0564
Antonio Egidio NardiInstitute of Psychiatry, Medical School, Federal University of Rio de Janeiro, Rio de Janeiro 21941-617, Brazil.ORCID 0000-0002-2152-4669
Daniele MaranoNational Institute of Women, Children and Adolescents Health Fernandes Figueira-Fiocruz, Rio de Janeiro 22250-020, Brazil.
Ana Carolina Carioca da CostaNational Institute of Women, Children and Adolescents Health Fernandes Figueira-Fiocruz, Rio de Janeiro 22250-020, Brazil.ORCID 0000-0002-9456-3319
Maria Elisabeth MoreiraNational Institute of Women, Children and Adolescents Health Fernandes Figueira-Fiocruz, Rio de Janeiro 22250-020, Brazil.ORCID 0000-0002-2034-0294

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro 26/200.254/2024
6 · The paper itself

Abstract

BACKGROUND/

objectivesThis study aimed to determine the percentage and duration of neutralizing antibodies against the Omicron variant in human milk after vaccination against SARS-CoV-2, considering the three different vaccine technologies approved in Brazil.

methodsA cross-sectional study was conducted with lactating women who received the complete vaccination cycle with available vaccines (AstraZeneca, Pfizer, CoronaVac, and Janssen). The participants resided in Rio de Janeiro, and samples were collected from April to October 2022. Breast milk was analyzed for evidence of neutralizing antibodies using specific assays for the Omicron variant.

resultsThe results showed that all types of vaccines were effective in inducing neutralizing antibodies in breast milk regardless of the vaccine technology used. There was no significant difference between women receiving two or three doses. Exclusive breastfeeding was significantly associated with higher percentages of neutralizing antibodies in breast milk compared to non-exclusive breastfeeding.

conclusionsThese findings reinforce the importance of breastfeeding as a strategy to provide passive protection to infants, especially where vaccination for children under six months of age is not recommended.

Indexed as

Antibodies, NeutralizingAntibodies, ViralBreast FeedingCOVID-19COVID-19 VaccinesImmunity, Maternally-AcquiredImmunization, PassiveMilk, HumanSARS-CoV-2AdultBrazilCross-Sectional StudiesFemaleHumansInfantInfant, NewbornAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesantibodiesbreastfeedingexclusiveneutralizingSARS-CoV-2vaccine

Identifiers

PMID39796564
PMCPMC11723047

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.