ArticleNutrients2024
Sex Differences in Gut Microbiota and Their Relation to Arterial Stiffness (MIVAS Study).
Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03900338 (Intestinal Microbiota and Its Relationship With Vascular Structure and Function and Cardiovascular Risk, Phase I), which is not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intestinal Microbiota and Its Relationship With Vascular Structure and Function and Cardiovascular Risk, Phase I (MIVAS Study)
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Role of Butyrate in People with Metabolic Dysfunction-Associated Steatotic Liver Disease and Related Metabolic Comorbidities: A Systematic Review.Current obesity reports · 2026Pooled it
- The impact of the number of remaining teeth on the risk of frailty: a meta-analysis.Odontology · 2026Pooled it
- Associations between gut microbiome and 24-hour blood pressure variability: a cross-sectional study highlighting sex differences and potential therapeutic targets.Gut microbiome (Cambridge, England) · 2026Article
- The association between the dietary index for gut microbiota and its components with cardiovascular disease risk: a cross-sectional study based on NHANES.Frontiers in nutrition · 2025Article
- Comparative efficacy and safety of vonoprazan versus esomeprazole-based high-dose dual therapies for first-lineTherapeutic advances in gastroenterology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
backgroundRecent research highlights the potential role of sex-specific variations in cardiovascular disease. The gut microbiome has been shown to differ between the sexes in patients with cardiovascular risk factors.
objectivesThe main objective of this study is to analyze the differences between women and men in the relationship between gut microbiota and measures of arterial stiffness.
methodsWe conducted a cross-sectional study in Spain, selecting 180 subjects (122 women, 58 men) aged between 45 and 74. Subjects with arterial stiffness were identified by the presence of at least one of the following: carotid-femoral pulse wave velocity (cf-PWV) above 12 mm/s, cardio-ankle vascular index (CAVI) above nine, or brachial-ankle pulse wave velocity (ba-PWV) above 17.5 m/s. All other cases were considered subjects without arterial stiffness. The composition of the gut microbiome in fecal samples was determined by 16S rRNA sequencing.
resultsWe found that women have a more diverse microbiome than men (Shannon,
conclusionsIn the Spanish population under study, women had higher microbiome diversity and potentially protective genera. The host's gender determines the influence of the same bacteria on arterial stiffness. TRIAL REGISTRATION NUMBER: NCT03900338.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.