Evidence map›Paper›PMID 39796484›Full record

ArticleNutrients2024

The Impact of Hypomagnesemia on the Long-Term Evolution After Kidney Transplantation.

Ioana Adela Ratiu, Corina Moisa, Luciana Marc, Nicu Olariu, Cristian Adrian Ratiu, Gabriel Cristian Bako, Anamaria Ratiu, Simona Fratila, Alin Cristian Teusdea, Mariana Ganea and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ioana Adela RatiuFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0003-0879-1903
Corina MoisaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Luciana MarcDivision of Nephrology, Department of Internal Medicine II, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Nicu OlariuDivision of Nephrology, Department of Internal Medicine II, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.
Cristian Adrian RatiuFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Gabriel Cristian BakoFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Anamaria RatiuFaculty of Dentistry, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, Victor Babeș Street 8, 400012 Cluj-Napoca, Romania.
Simona FratilaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0003-4900-4427
Alin Cristian TeusdeaFaculty of Environmental Protection, University of Oradea, 26th Gen. Magheru Avenue, 410087 Oradea, Romania.
Mariana GaneaFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.ORCID 0000-0003-4643-2151
Mirela IndriesFaculty of Medicine and Pharmacy, University of Oradea, 1st December Square 10, 410073 Oradea, Romania.
Lorena FilipFaculty of Pharmacy, University of Medicine and Pharmacy "Iuliu Hatieganu" Cluj-Napoca, Victor Babeș Street 8, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-9469-3546

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMagnesium plays a crucial role in immune function, influencing immunoglobulin synthesis, antibody-dependent cytolysis, and other immune processes. In renal transplant patients, magnesium deficiency is primarily induced by calcineurin inhibitor treatment, through the reduction of magnesium transporter proteins in the renal tubules, leading to magnesium loss.

methodsTo assess the correlation between serum magnesium levels and the long-term outcomes of renal graft and transplant recipients, we conducted a retrospective study on 87 patients who have had a transplant for more than 5 years, a period considered immunologically stable. We evaluated laboratory parameters such as glycemia, creatinine, total protein, and C-reactive protein (CRP), as well as demographic data, primary kidney disease, donor type, comorbidities, and infection incidence.

resultsThis study revealed clinical stability at over 5 years post-transplantation, with no significant differences between the 5-15 and over-15-years groups with regard to major comorbidities, except for HCV infection (

conclusionsHypomagnesemia correlates with increased infection risk in patients who received a renal transplant more than 5 years ago but does not significantly impact glycemic control or cardiovascular health.

Indexed as

Kidney TransplantationMagnesiumMagnesium DeficiencyAdultAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesMagnesiumimmunosuppressioninfectionskidney transplantationmagnesium

Identifiers

PMID39796484
PMCPMC11722560

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.