Evidence map›Paper›PMID 39796479›Full record

Trial reportNutrients2024

Postprandial Vascular Effects of a High Potassium Meal in Patients with Treated Hypertension.

Daniela Malta, Sam Esfandiari, Livia A Goldraich, Johane P Allard, Gary E Newton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Quantitative analysis of skeletal muscle contributions to ECF KAmerican journal of physiology. Cell physiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daniela MaltaSchool of Nutrition, Toronto Metropolitan University, 350 Victoria St., Toronto, ON M5B 2K3, Canada.ORCID 0000-0002-1617-1352
Sam EsfandiariInstitute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Livia A GoldraichDivision of Cardiology, Hospital de Clinicas de Porto Alegre, Porto Alegre 90035-903, Brazil.
Johane P AllardDepartment of Nutritional Sciences, University of Toronto, Fitzgerald Building, 150 College Street, Toronto, ON M5S 3E2, Canada.
Gary E NewtonInstitute of Medical Science, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is compelling evidence of an inverse association between potassium intake and blood pressure (BP). A potential mechanism for this effect may be dietary potassium-mediated augmentation of endothelium-dependent relaxation. To date, studies have investigated potassium intake supplementation over several weeks in healthy volunteers with variable results on vascular function. There is no assessment of the acute vascular effects of potassium supplementation achieved by the ingestion of potassium-rich food in a hypertensive population.

objectiveThe purpose of this study was to investigate the effect of a high potassium meal on postprandial endothelial function as measured by flow-mediated dilatation (FMD).

methodsWe performed an investigator-blinded randomized crossover trial in 33 treated hypertensive individuals. Participants consumed both a high (~2400 mg) and low (~543 mg) K

results33 individuals were included in the study (48% male, mean age 68). In the fasting state (Baseline), and at 60 min postprandial, radial artery FMD was not significantly different between the participants after consumption of either meal (baseline: high K

conclusionsThis study does not support our hypothesis that a single high K

Indexed as

Endothelium, VascularHypertensionPostprandial PeriodPotassium, DietaryAgedBlood PressureCross-Over StudiesDietary SupplementsFemaleHumansMaleMealsMiddle AgedVasodilationPotassium, Dietaryclinical nutritiondietary intakeendotheliumflow-mediated dilatationhypertensionpostprandialpotassiumrandomized crossover trialsodiumvasodilation

Identifiers

PMID39796479
PMCPMC11723007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.