Evidence map›Paper›PMID 39796455›Full record

ArticleNutrients2024

Predisposing Potential Risk Factors for Severe Anorexia Nervosa in Adolescents.

Elena Bozzola, Flavia Cirillo, Cristina Mascolo, Livia Antilici, Umberto Raucci, Benedetta Guarnieri, Annamaria Ventricelli, Elettra De Santis, Giulia Spina, Massimiliano Raponi and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elena BozzolaPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0001-5947-2414
Flavia CirilloPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Cristina MascoloPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Livia AntiliciPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Umberto RaucciPediatric Emergency Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-4881-2038
Benedetta GuarnieriPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Annamaria VentricelliPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Elettra De SantisPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Giulia SpinaPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-5685-5468
Massimiliano RaponiSanitary Direction, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.
Alberto VillaniPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-9120-0424
Maria Rosaria MarchiliPediatric Unit, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.ORCID 0000-0002-6787-8198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnorexia nervosa is a serious eating disorder that mainly affects children and adolescents. Most patients present with extreme body dissatisfaction and an obsessive focus on body weight and food. Anorexia nervosa is a complex and multifactorial condition characterised by biological, psychological, and social factors. However, studies that have explored the cumulative risk that predisposes to anorexia nervosa are limited. This study aims to explore the potential risk factors for a severe form of the disease in patients affected by anorexia nervosa and to identify whether they may interact and reinforce each other, contributing to the severity of the disorder.

methodsFor this study, we enrolled children and adolescents under 18 years of age hospitalised at IRCCS Bambino Gesù Pediatric Hospital, Rome, Italy, for anorexia nervosa from 1 December 2022 to 31 August 2024, identifying and analysing potential risk factors. Elevated shape and weight concerns were found in all patients. Psychiatric and neurodevelopment comorbidities were identified in 76 patients (51.35%), life stress events in 69 (46.62%), and a family history of eating and weight control behaviours in 39 (26.35%). Out of the sample size, 20.27% of patients did not live in a traditionally structured family. This study used the Kiddie-SADS-Present and Lifetime Version interview, the Coddington Life Events Scales, and the Trauma Symptom Checklist for Children questionnaires.

resultsPatients with an extreme or severe index of anorexia nervosa are more likely to have multiple predisposing factors. In detail, four predisposing factors were found in 18.6% of patients with an extreme severity index, in 15.5% of those with a severe score, and in 10.3 and 10.6% of those with a moderate and mild score, respectively.

conclusionsCumulative potential risk factors are more likely to be found in cases of severe course disease and patients hospitalised for anorexia. Prompt identification of predisposing factors and an effective plan of action are required to avoid a severe course disorder.

Indexed as

Anorexia NervosaAdolescentBody WeightChildFemaleHumansItalyMaleRisk FactorsSeverity of Illness Indexadolescentsanorexia nervosabody imagecumulative potential risk factors

Identifiers

PMID39796455
PMCPMC11723067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.