Evidence map›Paper›PMID 39796268›Full record

ArticleInternational journal of molecular sciences2025

Metal Ion Supplementation to Boost Melanin Production by

Odile Francesca Restaino, Talayeh Kordjazi, Francesco Tancredi, Paola Manini, Fabiana Lanzillo, Francesca Raganati, Antonio Marzocchella, Raffaele Porta, Loredana Mariniello

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Odile Francesca RestainoDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.
Talayeh KordjaziDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.
Francesco TancrediDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.
Paola ManiniDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0003-2842-5011
Fabiana LanzilloDepartment of Chemical, Materials and Production Engineering, Università degli Studi di Napoli Federico II, P. le V. Tecchio 80, 80125 Naples, Italy.
Francesca RaganatiDepartment of Chemical, Materials and Production Engineering, Università degli Studi di Napoli Federico II, P. le V. Tecchio 80, 80125 Naples, Italy.ORCID 0000-0002-9988-1164
Antonio MarzocchellaDepartment of Chemical, Materials and Production Engineering, Università degli Studi di Napoli Federico II, P. le V. Tecchio 80, 80125 Naples, Italy.ORCID 0000-0002-8124-9419
Raffaele PortaDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0003-4455-0664
Loredana MarinielloDepartment of Chemical Sciences, Università degli Studi di Napoli Federico II, Monte sant'Angelo Campus, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-6800-5890

Funding

This research was supported by the project PRIN 2022 PNRR "Sustainable Melanin production by Lignocellulose Agricultural byproducts for food safety applications (MeLA)" (D. D. n. 1289 del 04/08/2023), and funded by the European Union- NextGenerationEU" to PRIN 2022 PNRR P2022973R3
6 · The paper itself

Abstract

As Streptomycetes might produce melanin to survive in stressful environmental conditions, like under metal exposure, supplementing metal ions to the growth medium could be a wise strategy for boosting the production of the pigment. The aim of this study was to test, for the first time, the possibility of boosting

Indexed as

MelaninsMetalsStreptomycesCopper SulfateCulture MediaFermentationIonsMonophenol MonooxygenaseCopper SulfateCulture MediaeumelaninIonsMelaninsMetalsMonophenol MonooxygenasecoppereumelaninironL-tyrosinaseStreptomyces nashvillensis

Identifiers

PMID39796268
PMCPMC11720196

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.