Evidence map›Paper›PMID 39796126›Full record

ReviewInternational journal of molecular sciences2024

Biomarkers for the Molecular Diagnosis of IgE-Mediated Hymenoptera Venom Allergy in Clinical Practice.

Florin-Dan Popescu, Mariana Preda, Darío Antolín-Amérigo, Natalia Rodríguez-Otero, Elena Ramírez-Mateo, Sylwia Smolinska

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Homology Analysis ofToxins · 2026
    Article
  3. Review
  4. IgE levels correlate with FcFrontiers in allergy · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Florin-Dan PopescuFaculty of Medicine, Department of Allergology Nicolae Malaxa Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 022441 Bucharest, Romania.
Mariana PredaFaculty of Medicine, Department of Allergology Nicolae Malaxa Clinical Hospital, Carol Davila University of Medicine and Pharmacy, 022441 Bucharest, Romania.ORCID 0000-0001-7396-5688
Darío Antolín-AmérigoInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ramón y Cajal University Hospital, 28034 Madrid, Spain.
Natalia Rodríguez-OteroInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ramón y Cajal University Hospital, 28034 Madrid, Spain.ORCID 0000-0002-2572-7906
Elena Ramírez-MateoInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Ramón y Cajal University Hospital, 28034 Madrid, Spain.ORCID 0009-0000-4495-7945
Sylwia SmolinskaFaculty of Medicine, Department of Clinical Immunology, Wroclaw Medical University, 51-616 Wroclaw, Poland.ORCID 0000-0001-6736-2696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hymenoptera venom allergy (HVA) is a potentially life-threatening condition, making accurate diagnosis crucial for identifying significant IgE sensitizations and enabling effective venom immunotherapy. In this review, we provide a detailed overview of biomarkers for the molecular diagnosis of IgE-mediated hypersensitivity to Hymenoptera insect venoms in clinical practice, and we present, in a structured manner, their importance in differentiating genuine sensitizations versus cross-sensitizations using different diagnostic procedures. Updated algorithms are provided, along with the advantages and limitations of molecular diagnosis approaches. Geographical variations and rare species may pose further challenges in diagnosing and treating HVA, adding complexity to HVA management. This review informs readers about performing tailored diagnostics based on molecular allergen biomarkers and subsequent treatment strategies.

Indexed as

Arthropod VenomsBiomarkersHymenopteraHypersensitivityImmunoglobulin EAllergensAnimalsHumansAllergensArthropod VenomsBiomarkersImmunoglobulin EbiomarkersHymenoptera venom allergymolecular diagnosis

Identifiers

PMID39796126
PMCPMC11719524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.