Evidence map›Paper›PMID 39796055›Full record

ReviewInternational journal of molecular sciences2024

Harnessing Mesenchymal Stromal Cells for Advanced Wound Healing: A Comprehensive Review of Mechanisms and Applications.

Khrystyna Nasadiuk, Tomasz Kolanowski, Cezary Kowalewski, Katarzyna Wozniak, Tomasz Oldak, Natalia Rozwadowska

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Khrystyna NasadiukResearch and Development Department, Polski Bank Komórek Macierzystych S.A. (FamiCord Group), 00-867 Warsaw, Poland.
Tomasz KolanowskiResearch and Development Department, Polski Bank Komórek Macierzystych S.A. (FamiCord Group), 00-867 Warsaw, Poland.ORCID 0000-0003-3898-8272
Cezary KowalewskiDepartment of Dermatology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
Katarzyna WozniakDepartment of Dermatology, National Medical Institute of the Ministry of the Interior and Administration, 02-507 Warsaw, Poland.
Tomasz OldakResearch and Development Department, Polski Bank Komórek Macierzystych S.A. (FamiCord Group), 00-867 Warsaw, Poland.
Natalia RozwadowskaInstitute of Human Genetics, Polish Academy of Sciences, 60-479 Poznan, Poland.ORCID 0000-0002-5111-0870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds and injuries remain a substantial healthcare challenge, with significant burdens on patient quality of life and healthcare resources. Mesenchymal stromal cells (MSCs) present an innovative approach to enhance tissue repair and regeneration in the context of wound healing. The intrinsic presence of MSCs in skin tissue, combined with their roles in wound repair, ease of isolation, broad secretory profile, and low immunogenicity, makes them especially promising for treating chronic wounds. This review explores the current landscape of MSC application, focusing on preclinical and clinical data across chronic wounds, diabetic ulcers, burns, non-union bone fractures, lower extremity venous ulcers, pressure ulcers, and genetic skin conditions like epidermolysis bullosa. Special emphasis is given to the mechanisms through which MSCs exert their regenerative effects, underscoring their potential in advancing wound healing therapies and supporting the broader field of regenerative medicine.

Indexed as

Mesenchymal Stem CellsMesenchymal Stem Cell TransplantationWound HealingAnimalsHumansRegenerative Medicineburnschronic woundsdiabetic woundsepidermolysis bullosamesenchymal stromal cells (MSCs)non-union bone fractures

Identifiers

PMID39796055
PMCPMC11719717

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.