Evidence map›Paper›PMID 39796009›Full record

ArticleInternational journal of molecular sciences2024

The Role of Bone Marrow Stromal Cell Antigen 2 (BST2) in the Migration of Dendritic Cells to Lymph Nodes.

Sehoon Park, Eunbi Yi, Jaemyeong Jeon, Jinsoo Oh, Zhengmei Xu, Se-Ho Park

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sehoon ParkCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.ORCID 0000-0003-4254-6098
Eunbi YiCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Jaemyeong JeonCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Jinsoo OhCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Zhengmei XuCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.
Se-Ho ParkCollege of Life Sciences and Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Republic of Korea.ORCID 0000-0001-5018-8070

Funding

National Research Foundation of Korea NRF-2020M3A9I2108528 and NRF-2022R1A2C1011029.
6 · The paper itself

Abstract

Bone marrow stromal antigen 2 (BST2) is a host-restriction factor that plays multiple roles in the antiviral defense of innate immune responses, including the inhibition of viral particle release from virus-infected cells. BST2 may also be involved in the endothelial adhesion and migration of monocytes, but its importance in the immune system is still unclear. Immune cell adhesion and migration are closely related to the initiation of immune responses. In this study, we found that the expressions of the lymph node homing marker chemokine receptor 7 (CCR7) and an adhesion molecule intercellular adhesion molecule 1 (ICAM-1) in conventional dendritic cells (cDCs) were associated with BST2 expression. Interestingly,

Indexed as

Antigens, CDCell MovementDendritic CellsLymph NodesAnimalsBone Marrow Stromal Antigen 2Chemokine CCL19GPI-Linked ProteinsIntercellular Adhesion Molecule-1MiceMice, Inbred C57BLMice, KnockoutReceptors, CCR7T-LymphocytesAntigens, CDBone Marrow Stromal Antigen 2BST2 protein, mouseCcr7 protein, mouseChemokine CCL19GPI-Linked ProteinsIntercellular Adhesion Molecule-1Receptors, CCR7adhesion moleculesbone marrow stromal antigen 2 (BST2)cell migrationchemokine receptor 7 (CCR7)dendritic cellsintercellular adhesion molecule 1 (ICAM-1)

Identifiers

PMID39796009
PMCPMC11720714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.